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Literature DB >> 15569624

Histone modifications as key regulators of transcription.

Asad U Khan¹, Shankarling Krishnamurthy.

Abstract

Covalent modifications of the amino-termini of the core histones in nucleosomes have been shown to be one of the key regulatory mechanisms in transcription regulation. Recently, new roles for histone modifications have been uncovered for the efficient functioning of RNA Pol II. Besides acetylation, which is the most characterized to date these modifications comprise phosphorylation, methylation, and ubiquitination. This review gives comprehensive view of all the major histone modifications and their effect on transcriptional regulation, in Saccharomyces cerevisiae.

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Year: 2005 PMID： 15569624 DOI： 10.2741/1580

Source DB: PubMed Journal: Front Biosci ISSN： 1093-4715

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Cited

14 in total

1. Mitogen-activated protein kinase cascade-mediated histone H3 phosphorylation is critical for telomerase reverse transcriptase expression/telomerase activation induced by proliferation.

Authors: Zheng Ge; Cheng Liu; Magnus Björkholm; Astrid Gruber; Dawei Xu
Journal: Mol Cell Biol Date: 2006-01 Impact factor: 4.272

2. Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects.

Authors: Aldona A Karaczyn; Robert Y S Cheng; Gregory S Buzard; James Hartley; Dominic Esposito; Kazimierz S Kasprzak
Journal: Ann Clin Lab Sci Date: 2009 Impact factor: 1.256

3. Valproic acid prevents penile fibrosis and erectile dysfunction in cavernous nerve-injured rats.

Authors: Johanna L Hannan; Omer Kutlu; Bernard L Stopak; Xiaopu Liu; Fabio Castiglione; Petter Hedlund; Arthur L Burnett; Trinity J Bivalacqua
Journal: J Sex Med Date: 2014-03-18 Impact factor: 3.802

Review 4. Axotrophin and leukaemia inhibitory factor (LIF) in transplantation tolerance.

Authors: Su M Metcalfe
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2005-09-29 Impact factor: 6.237

Review 5. Maternal signals for progeny prevention against allergy and asthma.

Authors: Leigh Matthew Marsh; Petra Ina Pfefferle; Olaf Pinkenburg; Harald Renz
Journal: Cell Mol Life Sci Date: 2011-03-03 Impact factor: 9.261

6. Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1.

Authors: Michael Tibshirani; Miranda L Tradewell; Katie R Mattina; Sandra Minotti; Wencheng Yang; Hongru Zhou; Michael J Strong; Lawrence J Hayward; Heather D Durham
Journal: Hum Mol Genet Date: 2014-09-30 Impact factor: 6.150

Histone modifications as key regulators of transcription.

1. Mitogen-activated protein kinase cascade-mediated histone H3 phosphorylation is critical for telomerase reverse transcriptase expression/telomerase activation induced by proliferation.

2. Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects.

3. Valproic acid prevents penile fibrosis and erectile dysfunction in cavernous nerve-injured rats.

Review 4. Axotrophin and leukaemia inhibitory factor (LIF) in transplantation tolerance.

Review 5. Maternal signals for progeny prevention against allergy and asthma.

6. Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1.

7. Molecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells.

8. K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts.

Review 9. Protein modifications in transcription elongation.

10. Computational inference of mRNA stability from histone modification and transcriptome profiles.