| Literature DB >> 1556741 |
J L Thorne1, H Kishino, J Felsenstein.
Abstract
Our previous evolutionary model is generalized to permit approximate treatment of multiple-base insertions and deletions as well as regional heterogeneity of substitution rates. Parameter estimation and alignment procedures that incorporate these generalizations are developed. Simulations are used to assess the accuracy of the parameter estimation procedure and an example of an inferred alignment is included.Mesh:
Substances:
Year: 1992 PMID: 1556741 DOI: 10.1007/bf00163848
Source DB: PubMed Journal: J Mol Evol ISSN: 0022-2844 Impact factor: 2.395