Literature DB >> 155652

The blastogenic response of rabbit lymphocytes stimulated with autologous cells.

P Milthorp, M Richter.   

Abstract

Rabbit WBC and spleen cells respond with marked blastogenesis and mitosis when cultured with mitomycin-C treated autologous sacculus rotundus, appendix and Peyer's patches cells in the one-way rabbit mixed leucocyte reaction (MLR). A lesser response is observed using stimulating cells of the other lymphoid organs. The blastogenic response in the one-way 'autologous MLR' cannot be attributed to mitogenic factors released from the mitomycin-C treated stimulator cells since it is also observed in the 'two-way autologous MLR', using untreated stimulator cells. Several explanations are proposed to account for the 'autologous MLR'.

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Year:  1979        PMID： 155652      PMCID： PMC1457580     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  17 in total

1.  IMMUNE RESPONSE AND MITOSIS OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES IN VITRO.

Authors:  K HIRSCHHORN; F BACH; R L KOLODNY; I L FIRSCHEIN; N HASHEM
Journal:  Science       Date:  1963-11-29       Impact factor: 47.728

2.  Stimulation of autologous and allogeneic human T cells by B cells occurs through separate B-cell antigen systems.

Authors:  J B Smith
Journal:  Cell Immunol       Date:  1978-03-15       Impact factor: 4.868

3.  Mixed lymphocyte reactions in the rabbit using peripheral blood cells: the effects of cell preparation and skin grafting.

Authors:  H W Sheppard; S Sell; S M Poler; D D Redelman
Journal:  J Immunol Methods       Date:  1977       Impact factor: 2.303

4.  Lymphocyte interactions in autologous and allogeneic reactions.

Authors:  M Takasugi; M Kiuchi; G Opelz
Journal:  Transplant Proc       Date:  1977-03       Impact factor: 1.066

5.  Stimulation of lymphoid cells from normal and immune mice by syngeneic BALB/c plasma cell tumors.

Authors:  P J Boyer; J L Fahey
Journal:  J Immunol       Date:  1976-01       Impact factor: 5.422

6.  Differences between lymphocytes of leukemic and non-leukemic patients with respect to morphologic features, motility, and sensitivity to guinea pig serum.

Authors:  R SCHREK; W J DONNELLY
Journal:  Blood       Date:  1961-11       Impact factor: 22.113

7.  Lymphocyte transformation induced by autologous cells. V. Generation of immunologic memory and specificity during the autologous mixed lymphocyte reaction.

Authors:  M E Weksler; R Kozak
Journal:  J Exp Med       Date:  1977-12-01       Impact factor: 14.307

8.  Autologous stimulation of human lymphocyte subpopulation.

Authors:  G Opelz; M Kiuchi; M Takasugi; P I Terasaki
Journal:  J Exp Med       Date:  1975-11-01       Impact factor: 14.307

9.  Mixed lymphocyte reactivity and cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes in C57BL/10 congenic and B10-A recombinant mouse strains.

Authors:  G M Shearer; E C Lozner; T G Rehn; A M Schmitt-Verhulst
Journal:  J Exp Med       Date:  1975-04-01       Impact factor: 14.307

10.  Autologous mixed lymphocyte culture reactions and generation of cytotoxic T cells.

Authors:  R A Vande Stouwe; H G Kunkel; J P Halper; M E Weksler
Journal:  J Exp Med       Date:  1977-12-01       Impact factor: 14.307
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  1 in total

1.  Studies on the syngeneic mixed lymphocyte reaction. I. The ontogeny of the syngeneic mixed lymphocyte reaction in mice.

Authors:  J K Gutowski; M E Weksler
Journal:  Immunology       Date:  1982-08       Impact factor: 7.397
  1 in total

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