Literature DB >> 15564851

Elective neck dissection and survival in patients with squamous cell carcinoma of the oral cavity and oropharynx.

Umamaheswar Duvvuri1, Alfred A Simental, Gina D'Angelo, Jonas T Johnson, Robert L Ferris, William Gooding, Eugene N Myers.   

Abstract

OBJECTIVE/HYPOTHESIS: The utility of elective neck dissection in the management of patients with oral cavity and oropharyngeal cancer who present without neck metastases remains controversial. The study addressed the question of whether elective neck dissection improves regional control and survival in patients with squamous cell carcinoma of the oral cavity and oropharynx presenting with T1/T2 node-negative disease. STUDY
DESIGN: A nonrandomized, uncontrolled retrospective chart review.
METHODS: A nonrandomized, uncontrolled retrospective chart review was performed. Resection of the primary tumor was performed in all patients. The neck was observed in one group, and elective neck dissection was performed for patients in another group.
RESULTS: The study data indicated that elective neck dissection significantly improves regional control and regional recurrence-free survival. Elective neck dissection when compared with observation of the neck did not improve overall survival.
CONCLUSION: Elective neck dissection reduces regional recurrence and may extend disease-free survival.

Entities:  

Mesh:

Year:  2004        PMID: 15564851     DOI: 10.1097/01.mlg.0000149464.73080.20

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  22 in total

1.  Prognostic value of miR-375 and miR-214-3p in early stage oral squamous cell carcinoma.

Authors:  Angela J Yoon; Shuang Wang; Jing Shen; Nicolas Robine; Elizabeth Philipone; Martin W Oster; Albert Nam; Regina M Santella
Journal:  Am J Transl Res       Date:  2014-10-11       Impact factor: 4.060

2.  Results of selective neck dissection in the primary management of head and neck squamous cell carcinoma.

Authors:  Sandra Schmitz; Jean-Pascal Machiels; Birgit Weynand; Vincent Gregoire; Marc Hamoir
Journal:  Eur Arch Otorhinolaryngol       Date:  2008-07-22       Impact factor: 2.503

3.  Rapid molecular detection of metastatic head and neck squamous cell carcinoma as an intraoperative adjunct to sentinel lymph node biopsy.

Authors:  Robert L Ferris; Patrick Stefanika; Liqiang Xi; William Gooding; Raja R Seethala; Tony E Godfrey
Journal:  Laryngoscope       Date:  2012-03-23       Impact factor: 3.325

Review 4.  Outcome after elective neck dissection and observation for the treatment of the clinically node-negative neck (cN0) in squamous cell carcinoma of the oropharynx.

Authors:  R Böscke; B D Cakir; A S Hoffmann; S Wiegand; J Quetz; J E Meyer
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-05-10       Impact factor: 2.503

Review 5.  Minimally invasive techniques for head and neck malignancies: current indications, outcomes and future directions.

Authors:  Dana M Hartl; Alfio Ferlito; Carl E Silver; Robert P Takes; Sandro J Stoeckli; Carlos Suárez; Juan P Rodrigo; Andreas M Sesterhenn; Carl H Snyderman; David J Terris; Eric M Genden; Alessandra Rinaldo
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-05-12       Impact factor: 2.503

6.  Management of the Neck in Squamous Cell Carcinoma of the Oral Cavity and Oropharynx: ASCO Clinical Practice Guideline.

Authors:  Shlomo A Koyfman; Nofisat Ismaila; Doug Crook; Anil D'Cruz; Cristina P Rodriguez; David J Sher; Damian Silbermins; Erich M Sturgis; Terance T Tsue; Jared Weiss; Sue S Yom; F Christopher Holsinger
Journal:  J Clin Oncol       Date:  2019-02-27       Impact factor: 44.544

7.  Elective Neck Dissection in patients with stage T1-T2N0 carcinoma of the anterior tongue.

Authors:  D Mirea; R Grigore; D Safta; L Mirea; Cr Popescu; B Popescu; Svg Berteşteanu
Journal:  Hippokratia       Date:  2014-04       Impact factor: 0.471

8.  Sentinel lymph node biopsy versus selective neck dissection for detection of metastatic oral squamous cell carcinoma.

Authors:  Robert L Ferris; Dennis H Kraus
Journal:  Clin Exp Metastasis       Date:  2012-06-19       Impact factor: 5.150

Review 9.  Head and neck cancer.

Authors:  Athanassios Argiris; Michalis V Karamouzis; David Raben; Robert L Ferris
Journal:  Lancet       Date:  2008-05-17       Impact factor: 79.321

10.  Multi-institutional investigation of the prognostic value of lymph nodel yield in advanced-stage oral cavity squamous cell carcinoma.

Authors:  James J Jaber; Chad A Zender; Vikas Mehta; Kara Davis; Robert L Ferris; Pierre Lavertu; Rod Rezaee; Paul J Feustel; Jonas T Johnson
Journal:  Head Neck       Date:  2014-01-13       Impact factor: 3.147

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