Literature DB >> 15564305

Serial SimCoal: a population genetics model for data from multiple populations and points in time.

Christian N K Anderson1, Uma Ramakrishnan, Yvonne L Chan, Elizabeth A Hadly.   

Abstract

UNLABELLED: We present Serial SimCoal, a program that models population genetic data from multiple time points, as with ancient DNA data. An extension of SIMCOAL, it also allows simultaneous modeling of complex demographic histories, and migration between multiple populations. Further, we incorporate a statistical package to calculate relevant summary statistics, which, for the first time allows users to investigate the statistical power provided by, conduct hypothesis-testing with, and explore sample size limitations of ancient DNA data. AVAILABILITY: Source code and Windows/Mac executables at http://www.stanford.edu/group/hadlylab/ssc.html CONTACT: senka@stanford.edu.

Mesh：

Year:  2004        PMID： 15564305     DOI： 10.1093/bioinformatics/bti154

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


  65 in total

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