Literature DB >> 15562986

Facilitated assessment of unconsciousness from morphologic changes in the bilateral posterior tibial nerve cortical somatosensory evoked potential under total intravenous propofol anesthesia during spine surgery.

Daniel M Schwartz1, Anthony K Sestokas.   

Abstract

OBJECTIVE: To describe a unique morphologic feature of the bilateral posterior tibial nerve cortical somatosensory evoked potential, the S-wave, which varies systematically with propofol infusion rate and which appears to be useful in guiding adequate propofol concentration levels during spine surgery.
METHODS: Two illustrative cases were selected from a pool of 15,000 pediatric and adult patients (ages 8-85 years) who were undergoing corrective spine surgery in operating rooms of university and community hospitals. Anesthesia was maintained with a continuous intravenous infusion of propofol (125-225 microg/kg/min) along with intermittent boluses of narcotic and midazolam (1.0-2.0 mg) as needed. Characteristic metamorphosis of the bilateral posterior tibial nerve cortical somatosensory evoked potential, highlighted by the emergence of an additional middle-latency component labeled the S-wave, served as a neurophysiological marker of "light" propofol anesthesia prompting elevation of propofol infusion rate or bolus injection.
RESULTS: The S-wave was routinely abolished with increased propofol infusion rate or bolus injection. In all instances increased propofol concentration levels produced a characteristic morphologic change in the posterior tibial nerve cortical somatosensory evoked potential consistent with a return to adequate anesthetic depth. Selected cases presented herein compare the S-wave technique to BIS and illustrate the usefulness of the S-wave in identifying inadequate depth of propofol anesthesia.
CONCLUSIONS: The bilateral posterior tibial nerve cortical somatosensory evoked potential changes its morphology in predictable fashion with decreased depth of propofol anesthesia, allowing for anticipation of imminent anesthetic "lightening." It serves as a useful cross-check to Bispectral Index (BIS) or other "level of consciousness" EEG-based algorithms for monitoring depth of propofol anesthesia during prolonged corrective spine surgery.

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Year:  2004        PMID: 15562986     DOI: 10.1023/b:jocm.0000042992.40648.79

Source DB:  PubMed          Journal:  J Clin Monit Comput        ISSN: 1387-1307            Impact factor:   2.502


  17 in total

1.  A study of bispectral analysis and auditory evoked potential indices during propofol-induced hypnosis in volunteers: the effect of an episode of wakefulness on explicit and implicit memory.

Authors:  G Barr; R E Anderson; J G Jakobsson
Journal:  Anaesthesia       Date:  2001-09       Impact factor: 6.955

2.  Auditory evoked response and awareness: a study in volunteers at sub-MAC concentrations of isoflurane.

Authors:  D E Newton; C Thornton; K M Konieczko; C Jordan; N R Webster; N P Luff; C D Frith; C J Doré
Journal:  Br J Anaesth       Date:  1992-08       Impact factor: 9.166

3.  Influence of nitrous oxide on posterior tibial nerve cortical somatosensory evoked potentials.

Authors:  D M Schwartz; J A Schwartz; R E Pratt; L R Wierzbowski; A K Sestokas
Journal:  J Spinal Disord       Date:  1997-02

4.  Auditory evoked potentials during propofol anaesthesia in man.

Authors:  D Chassard; A Joubaud; A Colson; M Guiraud; C Dubreuil; V Banssillon
Journal:  Br J Anaesth       Date:  1989-05       Impact factor: 9.166

5.  Midazolam and awareness with recall during total intravenous anaesthesia.

Authors:  D R Miller; P G Blew; R J Martineau; K A Hull
Journal:  Can J Anaesth       Date:  1996-09       Impact factor: 5.063

6.  Mid-latency auditory evoked potentials during ketamine anaesthesia in humans.

Authors:  D Schwender; S Klasing; C Madler; E Pöppel; K Peter
Journal:  Br J Anaesth       Date:  1993-11       Impact factor: 9.166

7.  A multicenter study of bispectral electroencephalogram analysis for monitoring anesthetic effect.

Authors:  P S Sebel; E Lang; I J Rampil; P F White; R Cork; M Jopling; N T Smith; P S Glass; P Manberg
Journal:  Anesth Analg       Date:  1997-04       Impact factor: 5.108

8.  Bispectral Index (BIS) may not predict awareness reaction to intubation in surgical patients.

Authors:  Gerhard Schneider; Klaus Wagner; Wolfram Reeker; Frank Hänel; Christian Werner; Eberhard Kochs
Journal:  J Neurosurg Anesthesiol       Date:  2002-01       Impact factor: 3.956

9.  Power spectrum correlates of changes in consciousness during anesthetic induction with enflurane.

Authors:  W J Levy
Journal:  Anesthesiology       Date:  1986-06       Impact factor: 7.892

10.  Propofol blood concentration and the Bispectral Index predict suppression of learning during propofol/epidural anesthesia in volunteers.

Authors:  K Leslie; D I Sessler; M Schroeder; K Walters
Journal:  Anesth Analg       Date:  1995-12       Impact factor: 5.108

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