Literature DB >> 15557797

BRCA1 and BRCA2 in breast cancer predisposition and recombination control.

Ralph Scully1, Anyong Xie.   

Abstract

Hereditary predisposition to breast and ovarian cancer is determined in large part by loss-of-function mutations in one of two genes, BRCA1 and BRCA2 . Early discoveries that the two genes function in the control of homologous recombination and the prevention of genomic instability have been strongly supported by subsequent work. Our aim here is to highlight new advances in the study of BRCA1 and BRCA2 , and to place these advances in the context of existing knowledge.

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Year:  2004        PMID： 15557797     DOI： 10.1023/B:JOMG.0000048771.93906.3e

Source DB:  PubMed          Journal:  J Mammary Gland Biol Neoplasia        ISSN： 1083-3021            Impact factor:   2.673


  121 in total

1.  The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression.

Authors:  F E Kleiman; J L Manley
Journal:  Cell       Date:  2001-03-09       Impact factor: 41.582

2.  Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

Authors:  A A Davies; J Y Masson; M J McIlwraith; A Z Stasiak; A Stasiak; A R Venkitaraman; S C West
Journal:  Mol Cell       Date:  2001-02       Impact factor: 17.970

3.  A role for Saccharomyces cerevisiae histone H2A in DNA repair.

Authors:  J A Downs; N F Lowndes; S P Jackson
Journal:  Nature       Date:  2000 Dec 21-28       Impact factor: 49.962

4.  H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis.

Authors:  Oscar Fernandez-Capetillo; Shantha K Mahadevaiah; Arkady Celeste; Peter J Romanienko; R Daniel Camerini-Otero; William M Bonner; Katia Manova; Paul Burgoyne; André Nussenzweig
Journal:  Dev Cell       Date:  2003-04       Impact factor: 12.270

5.  Nine novel conserved motifs in BRCA1 identified by the chicken orthologue.

Authors:  B J Orelli; J M Logsdon; D K Bishop
Journal:  Oncogene       Date:  2001-07-19       Impact factor: 9.867

6.  Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development.

Authors:  V Joukov; J Chen; E A Fox; J B Green; D M Livingston
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-02       Impact factor: 11.205

7.  Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint.

Authors:  J A Tercero; J F Diffley
Journal:  Nature       Date:  2001-08-02       Impact factor: 49.962

8.  Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks.

Authors:  Arkady Celeste; Oscar Fernandez-Capetillo; Michael J Kruhlak; Duane R Pilch; David W Staudt; Alicia Lee; Robert F Bonner; William M Bonner; André Nussenzweig
Journal:  Nat Cell Biol       Date:  2003-07       Impact factor: 28.824

9.  BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.

Authors:  Haijuan Yang; Philip D Jeffrey; Julie Miller; Elspeth Kinnucan; Yutong Sun; Nicolas H Thoma; Ning Zheng; Phang-Lang Chen; Wen-Hwa Lee; Nikola P Pavletich
Journal:  Science       Date:  2002-09-13       Impact factor: 47.728

10.  Mutation and cancer: statistical study of retinoblastoma.

Authors:  A G Knudson
Journal:  Proc Natl Acad Sci U S A       Date:  1971-04       Impact factor: 11.205
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  2 in total

1.  Regulation of BRCA2 gene expression by the SLUG repressor protein in human breast cells.

Authors:  Manish K Tripathi; Smita Misra; Sheetal V Khedkar; Nalo Hamilton; Charletha Irvin-Wilson; Chakradhari Sharan; Linda Sealy; Gautam Chaudhuri
Journal:  J Biol Chem       Date:  2005-02-24       Impact factor: 5.157

Review 2.  The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular Locations.

Authors:  Beric R Henderson
Journal:  Scientifica (Cairo)       Date:  2012-10-18
  2 in total

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