| Literature DB >> 15551397 |
Bruno Marongiu1, Silvia Porcedda, Alessandra Piras, Antonella Rosa, Monica Deiana, Maria Assunta Dessì.
Abstract
The antioxidant activity of Melissa officinalis subsp. officinalis and of Melissa officinalis subsp. inodora extracts, obtained by using carbon dioxide under supercritical conditions was investigated. The samples were prepared in two steps. A preliminary extraction at 90 bar and 50 degrees C eliminated the essential oil, then a further extraction at 300 bar and 50 degrees C obtained the high molecular mass extract. These samples were tested for autoxidation and the iron or EDTA-mediated oxidation of linoleic acid at 37 degrees C in the absence of solvent, in in vitro systems. During linoleic acid autoxidation and its EDTA-mediated oxidation both M. officinalis and M. inodora extracts showed an antioxidant activity, and no significant differences in their efficacy were observed. None showed any prooxidant activity. Copyright 2004 John Wiley & Sons, Ltd.Entities:
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Year: 2004 PMID： 15551397 DOI： 10.1002/ptr.1549
Source DB: PubMed Journal: Phytother Res ISSN： 0951-418X Impact factor: 5.878