Literature DB >> 15550607

Symptoms and medical conditions in Australian veterans of the 1991 Gulf War: relation to immunisations and other Gulf War exposures.

H L Kelsall1, M R Sim, A B Forbes, D C Glass, D P McKenzie, J F Ikin, M J Abramson, L Blizzard, P Ittak.   

Abstract

AIMS: To investigate whether Australian Gulf War veterans have a higher than expected prevalence of recent symptoms and medical conditions that were first diagnosed in the period following the 1991 Gulf War; and if so, whether these effects were associated with exposures and experiences that occurred in the Gulf War.
METHODS: Cross-sectional study of 1456 Australian Gulf War veterans and a comparison group who were in operational units at the time of the Gulf War, but were not deployed to that conflict (n = 1588). A postal questionnaire was administered and the likelihood of the diagnosis of self-reported medical conditions was assessed and rated by a medical practitioner.
RESULTS: Gulf War veterans had a higher prevalence of all self-reported health symptoms than the comparison group, and more of the Gulf War veterans had severe symptoms. Increased symptom reporting was associated with several exposures, including having more than 10 immunisations, pyridostigmine bromide tablets, anti-biological warfare tablets, pesticides, insect repellents, reportedly being in a chemical weapons area, and stressful military service experiences in a strong dose-response relation. Gulf War veterans reported psychological (particularly post-traumatic stress disorder), skin, eye, and sinus conditions first diagnosed in 1991 or later more commonly than the comparison group. Over 90% of medical conditions reported by both study groups were rated by a medical practitioner as having a high likelihood of diagnosis.
CONCLUSION: More than 10 years after the 1991 Gulf War, Australian veterans self-report all symptoms and some medical conditions more commonly than the comparison group. Further analysis of the severity of symptoms and likelihood of the diagnosis of medical conditions suggested that these findings are not due to over-reporting or to participation bias.

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Year:  2004        PMID: 15550607      PMCID: PMC1740679          DOI: 10.1136/oem.2003.009258

Source DB:  PubMed          Journal:  Occup Environ Med        ISSN: 1351-0711            Impact factor:   4.402


  26 in total

1.  Strategies to assess validity of self-reported exposures during the Persian Gulf War. Portland Environmental Hazards Research Center.

Authors:  L A McCauley; S K Joos; P S Spencer; M Lasarev; T Shuell
Journal:  Environ Res       Date:  1999-10       Impact factor: 6.498

2.  Multiple chemical sensitivity and chronic fatigue syndrome in British Gulf War veterans.

Authors:  S Reid; M Hotopf; L Hull; K Ismail; C Unwin; S Wessely
Journal:  Am J Epidemiol       Date:  2001-03-15       Impact factor: 4.897

3.  Health effects of the 1991 Kuwait oil fires: a survey of US army troops.

Authors:  B P Petruccelli; M Goldenbaum; B Scott; R Lachiver; D Kanjarpane; E Elliott; M Francis; M A McDiarmid; D Deeter
Journal:  J Occup Environ Med       Date:  1999-06       Impact factor: 2.162

4.  State of health after deployment in the Persian Gulf. The Danish Gulf War Study.

Authors:  T Ishøy; P Suadicani; B Guldager; M Appleyard; H O Hein; F Gyntelberg
Journal:  Dan Med Bull       Date:  1999-11

5.  Determinants of long-term neuropsychological symptoms. The Danish Gulf War Study.

Authors:  P Suadicani; T Ishøy; B Guldager; M Appleyard; F Gyntelberg
Journal:  Dan Med Bull       Date:  1999-11

6.  Illnesses among United States veterans of the Gulf War: a population-based survey of 30,000 veterans.

Authors:  H K Kang; C M Mahan; K Y Lee; C A Magee; F M Murphy
Journal:  J Occup Environ Med       Date:  2000-05       Impact factor: 2.162

7.  Role of vaccinations as risk factors for ill health in veterans of the Gulf war: cross sectional study.

Authors:  M Hotopf; A David; L Hull; K Ismail; C Unwin; S Wessely
Journal:  BMJ       Date:  2000-05-20

8.  Prevalence and patterns of Gulf War illness in Kansas veterans: association of symptoms with characteristics of person, place, and time of military service.

Authors:  L Steele
Journal:  Am J Epidemiol       Date:  2000-11-15       Impact factor: 4.897

9.  Occupational risk factors for ill health in Gulf veterans of the United Kingdom.

Authors:  K Ismail; N Blatchley; M Hotopf; L Hull; I Palmer; C Unwin; A David; S Wessely
Journal:  J Epidemiol Community Health       Date:  2000-11       Impact factor: 3.710

10.  Posttraumatic stress disorder and depression symptomatology in a sample of Gulf War veterans: a prospective analysis.

Authors:  D J Erickson; J Wolfe; D W King; L A King; E J Sharkansky
Journal:  J Consult Clin Psychol       Date:  2001-02
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  21 in total

1.  Predictors of mental health service utilisation in a non-treatment seeking epidemiological sample of Australian adults.

Authors:  Vanessa Mills; Miranda Van Hooff; Jenelle Baur; Alexander C McFarlane
Journal:  Community Ment Health J       Date:  2011-10-13

2.  The health of Australian veterans of the 1991 Gulf War: factor analysis of self-reported symptoms.

Authors:  A B Forbes; D P McKenzie; A J Mackinnon; H L Kelsall; A C McFarlane; J F Ikin; D C Glass; M R Sim
Journal:  Occup Environ Med       Date:  2004-12       Impact factor: 4.402

3.  Pyridostigmine in the treatment of orthostatic hypotension.

Authors:  Jean-Michel Senard
Journal:  Clin Auton Res       Date:  2005-12       Impact factor: 4.435

4.  Immunological dysfunction, vaccination and Gulf War illness.

Authors:  Mark Peakman; Ania Skowera; Matthew Hotopf
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-04-29       Impact factor: 6.237

5.  The challenges of exposure assessment in health studies of Gulf War veterans.

Authors:  Deborah C Glass; Malcolm R Sim
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-04-29       Impact factor: 6.237

6.  Gulf War illness: a view from Australia.

Authors:  Malcolm Sim; Helen Kelsall
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-04-29       Impact factor: 6.237

7.  Multi-symptom illnesses, unexplained illness and Gulf War Syndrome.

Authors:  Khalida Ismail; Glyn Lewis
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-04-29       Impact factor: 6.237

Review 8.  Healthcare utilization and mortality among veterans of the Gulf War.

Authors:  Gregory C Gray; Han K Kang
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-04-29       Impact factor: 6.237

9.  Multiple vaccinations, health, and recall bias within UK armed forces deployed to Iraq: cohort study.

Authors:  Dominic Murphy; Matthew Hotopf; Simon Wessely
Journal:  BMJ       Date:  2008-06-30

10.  Traumatic events, other operational stressors and physical and mental health reported by Australian Defence Force personnel following peacekeeping and war-like deployments.

Authors:  Michael Waller; Susan A Treloar; Malcolm R Sim; Alexander C McFarlane; Annabel C L McGuire; Jonathan Bleier; Annette J Dobson
Journal:  BMC Psychiatry       Date:  2012-07-26       Impact factor: 3.630

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