Literature DB >> 15546724

Design, synthesis and anti-microbial activity of 1H-pyrazole carboxylates.

Radhakrishnan Sridhar1, Paramasivam T Perumal, Sundaresan Etti, Guruswamy Shanmugam, Mondikalipudur N Ponnuswamy, Vaiyapuri R Prabavathy, Narayanasamy Mathivanan.   

Abstract

In a SAR study, we have synthesized a few 1H-pyrazole carboxylate related microbicides using Vilsmeier reagent. The anti-microbial screening results of 1H-pyrazole-3-carboxylate are reported here for the first time. The effect of 1H-pyrazole carboxylates on the mycelial growth of plant pathogenic fungi is revealed. The first X-ray structure in the family of microbicidal 1H-pyrazole-4-carboxylates is presented.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15546724     DOI： 10.1016/j.bmcl.2004.09.066

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

1.  4-Chloro-5-[(5,5-dimethyl-4,5-dihydro-isoxazol-3-yl)sulfonyl-meth-yl]-3-methyl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazole.

Authors:  Hong-Ju Ma; Qian-Fei Zhao; Xiang-Dong Mei; Jun Ning
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-09-30

2.  Design, synthesis and evaluation of dihydrotriazine derivatives-bearing 5-aryloxypyrazole moieties as antibacterial agents.

Authors:  Tian-Yi Zhang; Chun-Shi Li; Ming-Yue Cui; Xue-Qian Bai; Jiang-Hui Chen; Ze-Wen Song; Bo Feng; Xue-Kun Liu
Journal:  Mol Divers       Date:  2020-03-14       Impact factor: 2.943

3.  Synthesis of some dihydropyrimidine-based compounds bearing pyrazoline moiety and evaluation of their antiproliferative activity.

Authors:  Fadi M Awadallah; Gary A Piazza; Bernard D Gary; Adam B Keeton; Joshua C Canzoneri
Journal:  Eur J Med Chem       Date:  2013-10-09       Impact factor: 6.514

4.  Synthesis of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes.

Authors:  Huanan Hu; Changhua Ge; Lisheng Ding; Anjiang Zhang
Journal:  Molecules       Date:  2010-10-25       Impact factor: 4.411

5.  Molecular Design, Synthesis, and Biological Evaluation of 2-Hydroxy-3-Chrysino Dithiocarbamate Derivatives.

Authors:  Pulabala Ramesh; Vankadari Srinivasa Rao; Yi-An Hong; P Muralidhar Reddy
Journal:  Molecules       Date:  2019-08-21       Impact factor: 4.411

6.  Prevention of secondary caries by a new antibacterial compound.

Authors:  Ali Eskandarizadeh; Iman Mohammadzadeh; Arash Shahravan; Mohammad Bavafa; Sina Kakooei; Molouk Torabi
Journal:  Dent Res J (Isfahan)       Date:  2020-01-21

7.  Catalytic and Multicomponent Reactions for Green Synthesis of Some Pyrazolone Compounds and Evaluation as Antimicrobial Agents.

Authors:  Hazim M Ali; Yasser A El-Ossaily; Saoud A Metwally; Ibrahim O Althobaiti; Hamud A Altaleb; Yousra A Naffea; Mahmoud S Tolba
Journal:  ACS Omega       Date:  2022-08-08

8.  Visible Light-Promoted Green and Sustainable Approach for One-Pot Synthesis of 4,4'-(Arylmethylene)bis(1H-pyrazol-5-ols), In Vitro Anticancer Activity, and Molecular Docking with Covid-19 Mpro.

Authors:  Anamika Gupta; Safia Iqbal; Mohd Kamil Hussain; Mohd Rehan Zaheer; Krapa Shankar
Journal:  ACS Omega       Date:  2022-09-14

9.  Synthesis of some novel 4-arylidene pyrazoles as potential antimicrobial agents.

Authors:  Poonam Khloya; Pawan Kumar; Arpana Mittal; Neeraj K Aggarwal; Pawan K Sharma
Journal:  Org Med Chem Lett       Date:  2013-08-28
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.