| Literature DB >> 15546488 |
Larry A Hembroff1, Margaret Holmes-Rovner, Celia E Wills.
Abstract
BACKGROUND: Prospective users of preventive therapies often must evaluate complex information about therapeutic risks and benefits. The purpose of this study was to evaluate the effect of relative and absolute risk information on patient decision-making in scenarios typical of health information for patients.Entities:
Mesh:
Year: 2004 PMID: 15546488 PMCID: PMC535806 DOI: 10.1186/1472-6947-4-20
Source DB: PubMed Journal: BMC Med Inform Decis Mak ISSN: 1472-6947 Impact factor: 2.796
Percentage of respondents who changed recommendation decision from baseline choice, by additional information condition
| Recommendation decision at baseline | |||||
| Take medication | Do not take medication | Don't Know | χ2 | ||
| 2. BC doubles | % Changed | 70.6% | 12.5% | 53.6% | 56.74** |
| (n) | (160) | (56) | (28) | ||
| 3. BC | % Changed | 34.7% | 9.1% | 59.3% | 20.11** |
| (n) | (144) | (44) | (27) | ||
| 4. HD < half | % Changed | 5.8% | 37.2% | 51.7% | 45.47** |
| (n) | (137) | (43) | (29) | ||
| 7. HD | % Changed | 4.5% | 36.5% | 28.6% | 42.97** |
| (n) | (177) | (63) | (21) | ||
| 5. BC doubles; HD < half | % Changed | 67.6% | 12.5% | 25.0% | 52.43** |
| (n) | (136) | (56) | (16) | ||
| 6. BC | % Changed | 19.1% | 35.3% | 64.9% | 29.93** |
| (n) | (141) | (34) | (37) | ||
| 8. BC doubles; HD | % Changed | 58.0% | 4.3% | 58.6% | 43.65** |
| (n) | (181) | (46) | (29) | ||
| 9. BC | % Changed | 42.8% | 27.5% | 54.5% | 6.92* |
| (n) | (159) | (69) | (22) | ||
* p < .05; ** p < .001
a The numbers in the left margins of these rows refer to the condition numbers as identified in Table 1.
% Recommending a friend take treatment for bone disease by nature of information given regarding effects on chances for breast cancer or heart disease
| Heart disease | |||||
| Breast cancer | None | Risk is reduced by more than half | Risk is reduced from 1 in 200 to 1 in 500 | ||
| None | % who recommend | Take | 66.8% | 73.3% | 71.6% |
| Don't take | 22.0% | 15.2% | 17.0% | ||
| Don't know | 11.2% | 11.5% | 11.5% | ||
| (n) | (937) | (210) | (262) | ||
| Risk doubles | % who recommend | Take | 21.2% | 22.3% | 31.3% |
| Don't take | 59.8% | 60.8% | 49.6% | ||
| Don't know | 19.0% | 16.9% | 19.1% | ||
| (n) | (245) | (209) | (257) | ||
| Risk increases from 1 in 10,000 to 2 in 10,000 | % who recommend | Take | 49.0% | 62.8% | 42.9% |
| Don't take | 40.0% | 26.1% | 42.9% | ||
| Don't know | 11.0% | 11.1% | 14.2% | ||
| (n) | (217) | (214) | (252) | ||
Results of Logistic Regressions of Recommending Taking Medication on Type of Disease and Format of Risk Communication (n = 930)
| Independent Variable | Coefficient (B) (s.e.) | Exp(B) |
| Format Risk Communication (Absolute Risk = 1) | -.089 (.208) | .915 |
| Type Disease (Breast Cancer = 1) | -2.326** (.221) | .098 |
| Interaction | 1.365** (.293) | 3.914 |
| Constant | 1.012** (.156) | |
| Model χ2 | 179.781** |
**p < .001
Results of logistic regressions of recommending taking medication on communicating breast cancer, heart disease risks in absolute terms (n = 926)
| Independent Variable | Coefficient (B) (s.e.) | Exp(B) |
| Breast cancer (absolute risk = 1) | 1.481** (.206) | 4.397 |
| Heart disease (absolute risk = 1) | .111 (.208) | 1.117 |
| Interaction | -.715** (.283) | .489 |
| Constant | -1.075** (.152) | |
| Model χ2 | 75.102** |
**p < .001
Results of logistic regression of "don't know" (DONTKNOW) and "not take the medication – don't know" (WRONG) answers on respondent demographic and health profile variables (n = 942)
| WRONG Answer | DONTKNOW Answer | |||
| Variable | B | Exp(B) | B | Exp(B) |
| Sex | -.176 | .839 | -.188 | .828 |
| Race | ||||
| African Americans | -.408 | .665 | -.193 | .824 |
| Other non-white | -.938 | .391 | -.539 | .584 |
| Hispanic | .988* | 2.687 | -.546 | .580 |
| Health fair or poor | -.538* | .584 | -.177 | .838 |
| No, only non-mainstream source health care | .155 | 1.167 | -.637 | .529 |
| Married or living with partner | .126 | 1.134 | -.017 | .984 |
| Where live | ||||
| Rural | -.054 | .947 | .242 | 1.274 |
| Small town | -.303 | .738 | .426 | 1.531 |
| Suburb | -.503 | .605 | -.235 | .791 |
| Currently employed | -.000 | 1.000 | -.635* | .530 |
| Current smoker | .445* | 1.561 | -.065 | .937 |
| Physically active | -.197 | .821 | .354 | 1.425 |
| Heavy drinker | -.496 | .609 | .094 | 1.099 |
| Age (in categories) | .152** | 1.164 | .129 | 1.138 |
| Level of education (in categories) | .240** | 1.273 | .151 | 1.163 |
| Children < 18 living in household | .795** | 2.214 | .714* | 2.042 |
| Currently overweight or obese | .062 | 1.064 | .010 | 1.010 |
| Constant | -1.973** | -3.271** | ||
| Chi-square = | 66.806** | 29.727* | ||
| df = | 18 | 18 | ||
* p < .05; ** p < .001
Representation of the baseline and incremental information conditions of the decision experiment
| None | Risk is reduced by more than half | Risk is reduced from 1 in 200 to1 in 500 | ||
| None | 1 Baseline Condition | 4 | 7 | |
| Risk Doubles | 2 | 5 | 8 | |
| Risk increases from 1 in 10,000 to 2 in 10,000 | 3 | 6 | 9 | |