Literature DB >> 15544545

Cellular and physiological effects of short-chain fatty acids.

Steven J Miller1.   

Abstract

Short chain fatty acids (SCFA) have multiple in vivo and in vitro effects including cell cycle arrest and induction of protein synthesis, differentiation, and apoptosis. Butyrate or derivatives have promise for treating inflammatory bowel disease and colon cancer. Genomic and proteomic analysis have generated new knowledge on function and applications for SCFA.

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Year:  2004        PMID： 15544545     DOI： 10.2174/1389557043403288

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  21 in total

1.  Short-chain fatty acids suppress lipopolysaccharide-induced production of nitric oxide and proinflammatory cytokines through inhibition of NF-κB pathway in RAW264.7 cells.

Authors:  Tengfei Liu; Jing Li; Yuxin Liu; Nan Xiao; Haitao Suo; Kun Xie; Chunliu Yang; Chen Wu
Journal:  Inflammation       Date:  2012-10       Impact factor: 4.092

2.  A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids.

Authors:  Xiaojiao Zheng; Yunping Qiu; Wei Zhong; Sarah Baxter; Mingming Su; Qiong Li; Guoxiang Xie; Brandon M Ore; Shanlei Qiao; Melanie D Spencer; Steven H Zeisel; Zhanxiang Zhou; Aihua Zhao; Wei Jia
Journal:  Metabolomics       Date:  2013-08-01       Impact factor: 4.290

Review 3.  Overview of the gastrointestinal microbiota.

Authors:  Vincent B Young; Thomas M Schmidt
Journal:  Adv Exp Med Biol       Date:  2008       Impact factor: 2.622

4.  Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.

Authors:  Prashant Mali; Bin-Kuan Chou; Jonathan Yen; Zhaohui Ye; Jizhong Zou; Sarah Dowey; Robert A Brodsky; Joyce E Ohm; Wayne Yu; Stephen B Baylin; Kosuke Yusa; Allan Bradley; David J Meyers; Chandrani Mukherjee; Philip A Cole; Linzhao Cheng
Journal:  Stem Cells       Date:  2010-04       Impact factor: 6.277

5.  Epigenetic mechanisms underlying diet-sourced compounds in the prevention and treatment of gastrointestinal cancer.

Authors:  Rebecca W Knackstedt; Vondina R Moseley; Michael J Wargovich
Journal:  Anticancer Agents Med Chem       Date:  2012-12       Impact factor: 2.505

6.  Growth inhibitory effect of 4-phenyl butyric acid on human gastric cancer cells is associated with cell cycle arrest.

Authors:  Long-Zhu Li; Hong-Xia Deng; Wen-Zhu Lou; Xue-Yan Sun; Meng-Wan Song; Jing Tao; Bing-Xiu Xiao; Jun-Ming Guo
Journal:  World J Gastroenterol       Date:  2012-01-07       Impact factor: 5.742

7.  Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+).

Authors:  Sonne R Srinivas; Puttur D Prasad; Nagavedi S Umapathy; Vadivel Ganapathy; Prem S Shekhawat
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2007-09-13       Impact factor: 4.052

Review 8.  Drugs or diet?--Developing novel therapeutic strategies targeting the free fatty acid family of GPCRs.

Authors:  H J Dranse; M E M Kelly; B D Hudson
Journal:  Br J Pharmacol       Date:  2013-10       Impact factor: 8.739

9.  Simultaneous quantification of straight-chain and branched-chain short chain fatty acids by gas chromatography mass spectrometry.

Authors:  Liqing He; Md Aminul Islam Prodhan; Fang Yuan; Xinmin Yin; Pawel K Lorkiewicz; Xiaoli Wei; Wenke Feng; Craig McClain; Xiang Zhang
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2018-06-18       Impact factor: 3.205

Review 10.  How Dysregulated Ion Channels and Transporters Take a Hand in Esophageal, Liver, and Colorectal Cancer.

Authors:  Christian Stock
Journal:  Rev Physiol Biochem Pharmacol       Date:  2021       Impact factor: 5.545
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