Literature DB >> 15537439

Osteoporosis prevalence and levels of treatment in primary care: the Australian BoneCare Study.

John Eisman1, Sharon Clapham, Linda Kehoe.   

Abstract

UNLABELLED: The level of recognition and treatment of osteoporosis is not well characterized in primary care. In data from a large sample of postmenopausal women attending 927 primary care physicians, 29% of women reported one or more fractures after menopause. The great majority (72%) were not on any osteoporosis-specific therapy.
INTRODUCTION: Osteoporosis is often first recognized at the time of a low-trauma fracture. However, by this stage, the risk of subsequent fractures has already risen substantially. Moreover, in many countries, only a small proportion of women, who have already sustained fractures, receive a treatment shown to reduce this increased risk of further fractures.
MATERIALS AND METHODS: This project was initiated to examine the prevalence of osteoporotic fractures, risk factors for osteoporosis, and use of antifracture therapy among postmenopausal Australian women. More than 88,000 women from 927 primary care physicians returned over 69,358 surveys. Of these, 57,088 reported the presence of a postmenopausal fracture or risk factors.
RESULTS: Among these randomly selected postmenopausal women, 29% reported having had one or more low-trauma fractures after menopause (44% substantiated in current records). One-third of these women reported multiple fractures. The prevalence of all types of fractures, except rib and ankle, increased with age and low body weight. Those who reported fractures were also more likely to report early menopause, corticosteroid use, and a family history of osteoporosis. Moreover, those with vertebral fractures were more likely to record height loss, kyphosis, and back pain. Physical inactivity, low calcium intake, and smoking had no consistent relationship with any fracture outcome. Of the women who reported a fracture after menopause, only 28% were on any specific therapy for osteoporosis, and 7% were on calcium alone. Of those who had been told they had osteoporosis by a doctor, 40% were receiving specific osteoporosis therapy.
CONCLUSIONS: In this large study of postmenopausal Australian women attending primary care physicians, 29% reported at least one low-trauma fracture after menopause. Less than one-third of these women were on specific treatment for osteoporosis, and only 40% were ever told they had osteoporosis. Therefore, osteoporotic fractures are common in postmenopausal Australian women, and few, despite their substantially increased risk of further fractures, are on any specific anti-osteoporotic therapy. These data support the need for more effective education for the community and medical practitioners of the clinical significance of osteoporotic fractures and alternatives for treatment.

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Year:  2004        PMID: 15537439     DOI: 10.1359/JBMR.040905

Source DB:  PubMed          Journal:  J Bone Miner Res        ISSN: 0884-0431            Impact factor:   6.741


  41 in total

Review 1.  Time to onset of efficacy in fracture reduction with current anti-osteoporosis treatments.

Authors:  Charles A Inderjeeth; Kien Chan; Kevin Kwan; Michelle Lai
Journal:  J Bone Miner Metab       Date:  2012-05-29       Impact factor: 2.626

2.  Hip fracture and other predictors of anti-osteoporosis drug use in Norway.

Authors:  H M Devold; A J Søgaard; A Tverdal; J A Falch; K Furu; H E Meyer
Journal:  Osteoporos Int       Date:  2012-07-10       Impact factor: 4.507

3.  Implementation of the Western Australian Osteoporosis Model of Care: a fracture liaison service utilising emergency department information systems to identify patients with fragility fracture to improve current practice and reduce re-fracture rates: a 12-month analysis.

Authors:  C A Inderjeeth; W D Raymond; A M Briggs; E Geelhoed; D Oldham; D Mountain
Journal:  Osteoporos Int       Date:  2018-04-27       Impact factor: 4.507

4.  Barriers to secondary fracture prevention in primary care.

Authors:  A S Mendis; K Ganda; M J Seibel
Journal:  Osteoporos Int       Date:  2017-06-29       Impact factor: 4.507

Review 5.  Interaction between bone and muscle in older persons with mobility limitations.

Authors:  L Ferrucci; M Baroni; A Ranchelli; F Lauretani; M Maggio; P Mecocci; C Ruggiero
Journal:  Curr Pharm Des       Date:  2014       Impact factor: 3.116

6.  Distribution of serum βCTX in a population-based study of postmenopausal women taking into account different anti-osteoporotic therapies (the FRODOS Cohort).

Authors:  Eduardo Kanterewicz; Pilar Peris; Emma Puigoriol; Aina Yáñez; Pau Rosique; Luis Del Rio
Journal:  J Bone Miner Metab       Date:  2012-12-08       Impact factor: 2.626

7.  A systematic review of the effectiveness of interventions to improve post-fracture investigation and management of patients at risk of osteoporosis.

Authors:  Elizabeth A Little; Martin P Eccles
Journal:  Implement Sci       Date:  2010-10-22       Impact factor: 7.327

8.  Bisphosphonate use is associated with reduced risk of myocardial infarction in patients with rheumatoid arthritis.

Authors:  Frederick Wolfe; Marcy B Bolster; Christopher M O'Connor; Kaleb Michaud; Kenneth W Lyles; Cathleen S Colón-Emeric
Journal:  J Bone Miner Res       Date:  2013-05       Impact factor: 6.741

9.  Improving osteoporosis management in general practice: a pharmacist-led drug use evaluation program.

Authors:  Edwin C K Tan; Johnson George; Kay Stewart; Rohan A Elliott
Journal:  Drugs Aging       Date:  2014-09       Impact factor: 3.923

10.  Multifaceted intervention to improve diagnosis and treatment of osteoporosis in patients with recent wrist fracture: a randomized controlled trial.

Authors:  Sumit R Majumdar; Jeffrey A Johnson; Finlay A McAlister; Debbie Bellerose; Anthony S Russell; David A Hanley; Don W Morrish; Walter P Maksymowych; Brian H Rowe
Journal:  CMAJ       Date:  2008-02-26       Impact factor: 8.262

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