Literature DB >> 15531468

Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas.

Fernando Gallardo, Manel Esteller, Ramon M Pujol, Carlota Costa, Teresa Estrach, Octavio Servitje.   

Abstract

p15(INK4b), p16(INK4a) and O(6)-methylguanine DNA methyltransferase (MGMT) gene hypermethylation was studied in 22 patients with primary cutaneous T-cell lymphomas (CTCL). p15(INK4b) and p16(INK4a) inactivation is present in early and advanced disease and seems to be independent of disease stage. MGMT inactivation may play a pathogenetic role in a subset of CTCL.

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Year:  2004        PMID： 15531468

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  14 in total

1.  Environmental chemical exposures and human epigenetics.

Authors:  Lifang Hou; Xiao Zhang; Dong Wang; Andrea Baccarelli
Journal:  Int J Epidemiol       Date:  2011-12-13       Impact factor: 7.196

2.  Promoter-Specific Hypomethylation Is Associated with Overexpression of PLS3, GATA6, and TWIST1 in the Sezary Syndrome.

Authors:  Henry K Wong; Heather Gibson; Timothy Hake; Susan Geyer; Julie Frederickson; Guido Marcucci; Michael A Caligiuri; Pierluigi Porcu; Anjali Mishra
Journal:  J Invest Dermatol       Date:  2015-03-25       Impact factor: 8.551

Review 3.  Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules.

Authors:  Pilar Blancafort; Jian Jin; Stephen Frye
Journal:  Mol Pharmacol       Date:  2012-11-13       Impact factor: 4.436

Review 4.  Methotrexate and Pralatrexate.

Authors:  Gary S Wood; Jianqiang Wu
Journal:  Dermatol Clin       Date:  2015-08-01       Impact factor: 3.478

Review 5.  Cutaneous T cell lymphoma.

Authors:  Reinhard Dummer; Maarten H Vermeer; Julia J Scarisbrick; Youn H Kim; Connor Stonesifer; Cornelis P Tensen; Larisa J Geskin; Pietro Quaglino; Egle Ramelyte
Journal:  Nat Rev Dis Primers       Date:  2021-08-26       Impact factor: 52.329

6.  Notch1 Pathway Activation Results from the Epigenetic Abrogation of Notch-Related MicroRNAs in Mycosis Fungoides.

Authors:  Fernando Gallardo; Juan Sandoval; Angel Díaz-Lagares; Ricard Garcia; Teresa D'Altri; Jessica González; Victor Alegre; Octavio Servitje; Ana-Belén Crujeiras; Ólafur-Andri Stefánsson; Blanca Espinet; Maria-Inmaculada Hernández; Beatriz Bellosillo; Manel Esteller; Ramon-Maria Pujol; Anna Bigas; Lluis Espinosa
Journal:  J Invest Dermatol       Date:  2015-08-24       Impact factor: 8.551

7.  MicroRNA-16 mediates the regulation of a senescence-apoptosis switch in cutaneous T-cell and other non-Hodgkin lymphomas.

Authors:  A Kitadate; S Ikeda; K Teshima; M Ito; I Toyota; N Hasunuma; N Takahashi; T Miyagaki; M Sugaya; H Tagawa
Journal:  Oncogene       Date:  2015-12-07       Impact factor: 9.867

8.  Hypomethylation of the promoter region drives ectopic expression of TMEM244 in Sézary cells.

Authors:  Katarzyna Iżykowska; Karolina Rassek; Magdalena Żurawek; Karina Nowicka; Julia Paczkowska; Iwona Ziółkowska-Suchanek; Marta Podralska; Agnieszka Dzikiewicz-Krawczyk; Monika Joks; Karolina Olek-Hrab; Maciej Giefing; Grzegorz K Przybylski
Journal:  J Cell Mol Med       Date:  2020-08-14       Impact factor: 5.310

9.  Quantitative gene analysis of methylation and expression (Q-GAME) in fresh or fixed cells and tissues.

Authors:  Jianqiang Wu; Katrin A Salva; Nathalie Stutz; B Jack Longley; Vladimir S Spiegelman; Gary S Wood
Journal:  Exp Dermatol       Date:  2014-05       Impact factor: 3.960

10.  Efficacy and safety of the third-generation chloroethylnitrosourea fotemustine for the treatment of chemorefractory T-cell lymphomas.

Authors:  Gaetano Corazzelli; Ferdinando Frigeri; Manuela Arcamone; Luigi Aloj; Gaetana Capobianco; Cristina Becchimanzi; Emanuela Morelli; Francesco Volzone; Gianpaolo Marcacci; Filippo Russo; Rosaria De Filippi; Secondo Lastoria; Antonio Pinto
Journal:  Eur J Haematol       Date:  2011-07-31       Impact factor: 2.997
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