Literature DB >> 15528052

A clinically meaningful difference was generated for a performance measure of recovery from hip fracture.

W G Hawkes1, G R Williams, S Zimmerman, P Lapuerta, T Li, D Orwig, L Wehren, J R Hebel, J Magaziner.   

Abstract

BACKGROUND AND
OBJECTIVE: The Lower Extremity Gain Scale (LEGS) is a performance measure of tasks that are often impaired in hip fracture patients. This study was designed to determine a clinically meaningful difference in LEGS.
METHODS: The population was 139 female patients (age >65 years) admitted to Baltimore hospitals. Recovery levels were estimated by fitting trajectory curves for the cohort for the 12 months post fracture. The clinically meaningful difference was evaluated using an anchor-based approach, examining the relationship between the LEGS recovery level and age. A second, distribution-based method used an effect size of .20.
RESULTS: According to our model, a difference of 5 years in age corresponded to a difference of 1.6-3.6 points in LEGS scores. The standard deviation for LEGS at 12 months was 8.0; thus, Cohen's effect size of 0.2 would equate to a difference of 1.6 points.
CONCLUSION: This suggests that a clinically meaningful difference in the LEGS scores for a population in this age range would be 2-3 points.

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Mesh:

Year:  2004        PMID: 15528052     DOI: 10.1016/j.jclinepi.2004.02.010

Source DB:  PubMed          Journal:  J Clin Epidemiol        ISSN: 0895-4356            Impact factor:   6.437


  7 in total

1.  The association between body mass index, weight loss and physical function in the year following a hip fracture.

Authors:  L Reider; W Hawkes; J R Hebel; C D'Adamo; J Magaziner; R Miller; D Orwig; D E Alley
Journal:  J Nutr Health Aging       Date:  2013-01       Impact factor: 4.075

2.  Genotype, resilience and function and physical activity post hip fracture.

Authors:  Barbara Resnick; N Jennifer Klinedinst; Laura Yerges-Armstrong; Jay Magaziner; Denise Orwig; Marc C Hochberg; Ann L Gruber-Baldini; Susan G Dorsey
Journal:  Int J Orthop Trauma Nurs       Date:  2019-03-23

3.  Weighted estimating equations for longitudinal studies with death and non-monotone missing time-dependent covariates and outcomes.

Authors:  Michelle Shardell; Ram R Miller
Journal:  Stat Med       Date:  2008-03-30       Impact factor: 2.373

4.  Association between interleukin-6 and lower extremity function after hip fracture--the role of muscle mass and strength.

Authors:  Ram R Miller; Michelle D Shardell; Gregory E Hicks; Anne R Cappola; William G Hawkes; Janet A Yu-Yahiro; Jay Magaziner
Journal:  J Am Geriatr Soc       Date:  2008-04-11       Impact factor: 5.562

5.  Repeat falls and the recovery of social participation in the year post-hip fracture.

Authors:  Ram R Miller; Shoshana H Ballew; Michelle D Shardell; Gregory E Hicks; William G Hawkes; Barbara Resnick; Jay Magaziner
Journal:  Age Ageing       Date:  2009-07-08       Impact factor: 10.668

6.  Estimating the minimal clinically important difference for the Physical Component Summary of the Short Form 36 for patients with stroke.

Authors:  Vivian Fu; Mark Weatherall; Harry McNaughton
Journal:  J Int Med Res       Date:  2021-12       Impact factor: 1.671

7.  Validation of the Indonesian version of the foot and ankle score in patients with chronic lateral ankle instability.

Authors:  I Putu Gde Surya Adhitya; Wen-Yu Yu; Putu Ayu Sita Saraswati; I Made Niko Winaya; Mau-Roung Lin
Journal:  J Foot Ankle Res       Date:  2021-08-04       Impact factor: 2.303

  7 in total

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