Literature DB >> 15525541

Matrix metalloproteinases and the gut - new roles for old enzymes.

Sylvia L F Pender1, Thomas T MacDonald.   

Abstract

Matrix metalloproteinases (MMPs) are a family of neutral proteases with the ability to degrade all components of extracellular matrix. To date, more than 24 different human MMPs have been identified. MMP activity is important in diseases such as arthritis, atherosclerosis, periodontal diseases and cancer. Recent data suggest that MMPs are involved in tissue injury and healing in the human gut.

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Year:  2004        PMID： 15525541     DOI： 10.1016/j.coph.2004.06.005

Source DB:  PubMed          Journal:  Curr Opin Pharmacol        ISSN： 1471-4892            Impact factor:   5.547


  19 in total

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