| Literature DB >> 15523479 |
Michael S Cosgrove1, Jef D Boeke, Cynthia Wolberger.
Abstract
Post-translational modifications of the histone tails are correlated with distinct chromatin states that regulate access to DNA. Recent proteomic analyses have revealed several new modifications in the globular nucleosome core, many of which lie at the histone-DNA interface. We interpret these modifications in light of previously published data and propose a new and testable model for how cells implement the histone code by modulating nucleosome dynamics.Mesh：
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Year: 2004 PMID： 15523479 DOI： 10.1038/nsmb851
Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369