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Literature DB >> 15520846

Embryonic death and the creation of human embryonic stem cells.

Abstract

The creation of human embryonic stem cells through the destruction of a human embryo pits the value of a potential therapeutic tool against that of an early human life. This contest of values has resulted in a polarized debate that neglects areas of common interest and perspective. We suggest that a common ground for pursuing research on human embryonic stem cells can be found by reconsidering the death of the human embryo and by applying to this research the ethical norms of essential organ donation.

Entities: Disease Species

Keywords: Biomedical and Behavioral Research; Genetics and Reproduction

Mesh：

Year: 2004 PMID： 15520846 PMCID： PMC524233 DOI： 10.1172/JCI23065

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

9 in total

1. Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization.

Authors: L Voullaire; H Slater; R Williamson; L Wilton
Journal: Hum Genet Date: 2000-02 Impact factor: 4.132

2. From intestine to muscle: nuclear reprogramming through defective cloned embryos.

Authors: J A Byrne; S Simonsson; J B Gurdon
Journal: Proc Natl Acad Sci U S A Date: 2002-04-23 Impact factor: 11.205

3. In re Long Island Jewish Medical Center.

Authors:
Journal: Wests N Y Suppl Date: 1996-02-28

Review 4. Prometheus's vulture and the stem-cell promise.

Authors: Nadia Rosenthal
Journal: N Engl J Med Date: 2003-07-17 Impact factor: 91.245

5. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4.

Authors: J Nichols; B Zevnik; K Anastassiadis; H Niwa; D Klewe-Nebenius; I Chambers; H Schöler; A Smith
Journal: Cell Date: 1998-10-30 Impact factor: 41.582

6. Fluorescent in-situ hybridization on human embryos showing cleavage arrest after freezing and thawing.

Authors: H Laverge; J Van der Elst; P De Sutter; M R Verschraegen-Spae; A De Paepe; M Dhont
Journal: Hum Reprod Date: 1998-02 Impact factor: 6.918

7. Human blastocysts from aggregated mononucleated cells of two or more non-viable zygote-derived embryos.

Authors: Mina Alikani; Steen M Willadsen
Journal: Reprod Biomed Online Date: 2002 Jul-Aug Impact factor: 3.828

8. A definition of irreversible coma. Report of the Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death.

Authors:
Journal: JAMA Date: 1968-08-05 Impact factor: 56.272

9. Embryonic stem cell lines derived from human blastocysts.

Authors: J A Thomson; J Itskovitz-Eldor; S S Shapiro; M A Waknitz; J J Swiergiel; V S Marshall; J M Jones
Journal: Science Date: 1998-11-06 Impact factor: 47.728

9 in total

18 in total

Embryonic death and the creation of human embryonic stem cells.

1. Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization.

2. From intestine to muscle: nuclear reprogramming through defective cloned embryos.

3. In re Long Island Jewish Medical Center.

Review 4. Prometheus's vulture and the stem-cell promise.

5. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4.

6. Fluorescent in-situ hybridization on human embryos showing cleavage arrest after freezing and thawing.

7. Human blastocysts from aggregated mononucleated cells of two or more non-viable zygote-derived embryos.

8. A definition of irreversible coma. Report of the Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death.

9. Embryonic stem cell lines derived from human blastocysts.

Review 1. Is a consensus possible on stem cell research? Moral and political obstacles.

Review 2. What's in a name? Embryos, entities, and ANTities in the stem cell debate.

Review 3. Potential for access to embryonic-like cells from human umbilical cord blood.

Review 4. Alternative sources of pluripotent stem cells: altered nuclear transfer.

5. From embryonic stem cells to iPS - an ethical perspective.

6. The Shortage of Malaysian Stem Cell Ethics in Mainstream Database: a Preliminary Study.

Review 7. Wishful thinking will not obviate embryo use.

Review 8. Sources of stem cells for regenerative medicine.

Review 9. Embryonic stem cells or induced pluripotent stem cells? A DNA integrity perspective.

Review 10. Parthenogenesis as an approach to pluripotency: advantages and limitations involved.