| Literature DB >> 15504881 |
Giovanni Di Bonaventura1, Ilaria Spedicato, Carla Picciani, Domenico D'Antonio, Raffaele Piccolomini.
Abstract
Time-kill and postantifungal effect (PAFE) of amphotericin B, caspofungin, fluconazole, and voriconazole were determined against clinical isolates of Candida guilliermondii, Candida kefyr, and Candida lusitaniae. Azoles displayed fungistatic activity and no measurable PAFE, regardless of the concentration tested. Amphotericin B and caspofungin demonstrated concentration-dependent fungicidal activity, although amphotericin B only produced a significant dose-dependent PAFE against all isolates tested.Entities:
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Year: 2004 PMID: 15504881 PMCID: PMC525414 DOI: 10.1128/AAC.48.11.4453-4456.2004
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191