Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 OXA-60, a chromosomal, inducible, and imipenem-hydrolyzing class D beta-lactamase from Ralstonia pickettii.

Literature DB >> 15504844

OXA-60, a chromosomal, inducible, and imipenem-hydrolyzing class D beta-lactamase from Ralstonia pickettii.

Delphine Girlich¹, Thierry Naas, Patrice Nordmann.

Abstract

A chromosomally encoded oxacillinase, OXA-22, had been characterized from Ralstonia pickettii PIC-1 that did not explain by itself the resistance profile of this strain to beta-lactams. Thus, further analysis of the genetic background of this species led to the identification of another oxacillinase, OXA-60, that was expressed only after beta-lactam induction. This chromosomally encoded oxacillinase shared 19% amino acid identity with OXA-22. It has a narrow-spectrum hydrolysis profile that includes imipenem. OXA-60-like enzymes were identified in several R. pickettii strains. Gene inactivation and induction studies of the bla(OXA-60) and bla(OXA-22) genes in R. pickettii identified the relative contribution of each oxacillinase to the resistance profile of R. pickettii to beta-lactams.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2004 PMID： 15504844 PMCID： PMC525441 DOI： 10.1128/AAC.48.11.4217-4225.2004

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

40 in total

1. Genome sequence of the plant pathogen Ralstonia solanacearum.

Authors: M Salanoubat; S Genin; F Artiguenave; J Gouzy; S Mangenot; M Arlat; A Billault; P Brottier; J C Camus; L Cattolico; M Chandler; N Choisne; C Claudel-Renard; S Cunnac; N Demange; C Gaspin; M Lavie; A Moisan; C Robert; W Saurin; T Schiex; P Siguier; P Thébault; M Whalen; P Wincker; M Levy; J Weissenbach; C A Boucher
Journal: Nature Date: 2002-01-31 Impact factor: 49.962

2. Escherichia coli CreBC is a global regulator of gene expression that responds to growth in minimal media.

Authors: M B Avison; R E Horton; T R Walsh; P M Bennett
Journal: J Biol Chem Date: 2001-05-11 Impact factor: 5.157

3. Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110.

Authors: Takakazu Kaneko; Yasukazu Nakamura; Shusei Sato; Kiwamu Minamisawa; Toshiki Uchiumi; Shigemi Sasamoto; Akiko Watanabe; Kumi Idesawa; Mayumi Iriguchi; Kumiko Kawashima; Mitsuyo Kohara; Midori Matsumoto; Sayaka Shimpo; Hisae Tsuruoka; Tsuyuko Wada; Manabu Yamada; Satoshi Tabata
Journal: DNA Res Date: 2002-12-31 Impact factor: 4.458

4. Characterization of OXA-25, OXA-26, and OXA-27, molecular class D beta-lactamases associated with carbapenem resistance in clinical isolates of Acinetobacter baumannii.

Authors: M Afzal-Shah; N Woodford; D M Livermore
Journal: Antimicrob Agents Chemother Date: 2001-02 Impact factor: 5.191

5. Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.

Authors: B Goodner; G Hinkle; S Gattung; N Miller; M Blanchard; B Qurollo; B S Goldman; Y Cao; M Askenazi; C Halling; L Mullin; K Houmiel; J Gordon; M Vaudin; O Iartchouk; A Epp; F Liu; C Wollam; M Allinger; D Doughty; C Scott; C Lappas; B Markelz; C Flanagan; C Crowell; J Gurson; C Lomo; C Sear; G Strub; C Cielo; S Slater
Journal: Science Date: 2001-12-14 Impact factor: 47.728

6. The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.

Authors:
Journal: Proc Natl Acad Sci U S A Date: 2003-09-18 Impact factor: 11.205

7. Genetic linkage of the penicillinase gene, amp, and blrAB, encoding the regulator of beta-lactamase expression in Aeromonas spp.

Authors: Pannika Niumsup; Alan M Simm; Kurshid Nurmahomed; Timothy R Walsh; Peter M Bennett; Matthew B Avison
Journal: J Antimicrob Chemother Date: 2003-05-13 Impact factor: 5.790

8. Genetic and functional analysis of the chromosome-encoded carbapenem-hydrolyzing oxacillinase OXA-40 of Acinetobacter baumannii.

Authors: Claire Héritier; Laurent Poirel; Daniel Aubert; Patrice Nordmann
Journal: Antimicrob Agents Chemother Date: 2003-01 Impact factor: 5.191

9. Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae.

Authors: Laurent Poirel; Claire Héritier; Venus Tolün; Patrice Nordmann
Journal: Antimicrob Agents Chemother Date: 2004-01 Impact factor: 5.191

10. Chromosome-encoded ambler class D beta-lactamase of Shewanella oneidensis as a progenitor of carbapenem-hydrolyzing oxacillinase.

Authors: Laurent Poirel; Claire Héritier; Patrice Nordmann
Journal: Antimicrob Agents Chemother Date: 2004-01 Impact factor: 5.191

16 in total

OXA-60, a chromosomal, inducible, and imipenem-hydrolyzing class D beta-lactamase from Ralstonia pickettii.

1. Genome sequence of the plant pathogen Ralstonia solanacearum.

2. Escherichia coli CreBC is a global regulator of gene expression that responds to growth in minimal media.

3. Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110.

4. Characterization of OXA-25, OXA-26, and OXA-27, molecular class D beta-lactamases associated with carbapenem resistance in clinical isolates of Acinetobacter baumannii.

5. Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.

6. The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.

7. Genetic linkage of the penicillinase gene, amp, and blrAB, encoding the regulator of beta-lactamase expression in Aeromonas spp.

8. Genetic and functional analysis of the chromosome-encoded carbapenem-hydrolyzing oxacillinase OXA-40 of Acinetobacter baumannii.

9. Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae.

10. Chromosome-encoded ambler class D beta-lactamase of Shewanella oneidensis as a progenitor of carbapenem-hydrolyzing oxacillinase.

Review 1. Carbapenemases: the versatile beta-lactamases.

2. Characterization of the naturally occurring oxacillinase of Acinetobacter baumannii.

Review 3. Ralstonia spp.: emerging global opportunistic pathogens.

4. Novel carbapenem-hydrolyzing oxacillinase OXA-62 from Pandoraea pnomenusa.

5. Ralstonia pickettii bloodstream infections at a Brazilian cancer institution.

6. Characterization of a naturally occurring class D beta-lactamase from Achromobacter xylosoxidans.

Review 7. Diversity, epidemiology, and genetics of class D beta-lactamases.

8. Lobar pneumonia caused by Ralstonia pickettii in a sixty-five-year-old Han Chinese man: a case report.

9. Genome Sequence of a Carbapenem-Resistant Strain of Ralstonia mannitolilytica.

10. Expression of blaA underlies unexpected ampicillin-induced cell lysis of Shewanella oneidensis.