Literature DB >> 15500075

Effects of flavonoids on the resistance of microsomes to lipid peroxidation in vitro and ex vivo.

L V Kravchenko1, S V Morozov, V A Tutel'yan.   

Abstract

Incubation of rat liver microsomes with preparations of grape flavonoids, dihydroquercetin, and silibinin increased their resistance to lipid peroxidation induced by NADPH-Fe2+. This was manifested in less pronounced accumulation of lipid peroxidation products and changes in activity of microsomal enzymes induced by lipid peroxidation. In vitro antioxidant activity of grape flavonoids markedly surpassed that of dihydroquercetin and silibinin. Addition of flavonoids into fodder led to moderate, statistically significant, and similar increase in the resistance of rat liver microsomes to ex vivo induced lipid peroxidation.

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Year:  2003        PMID： 15500075     DOI： 10.1023/b:bebm.0000020207.67705.59

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  6 in total

1.  Effect of Dihydroquercetin on Energy Metabolism in LPS-Induced Inflammatory Mice.

Authors:  Xiaoying Yu; Saddam Hussein; Lijia Li; Qingyu Liu; Zhibin Ban; Hailong Jiang
Journal:  Biomed Res Int       Date:  2022-07-04       Impact factor: 3.246

2.  Silibinin ameliorates oxidative stress induced aberrant crypt foci and lipid peroxidation in 1, 2 dimethylhydrazine induced rat colon cancer.

Authors:  Nagarajan Sangeetha; Selvaraj Aranganathan; Namasivayam Nalini
Journal:  Invest New Drugs       Date:  2009-03-10       Impact factor: 3.850

3.  The effect of a silybin-vitamin e-phospholipid complex on nonalcoholic fatty liver disease: a pilot study.

Authors:  Carmela Loguercio; Alessandro Federico; Marco Trappoliere; Concetta Tuccillo; Ilario de Sio; Agnese Di Leva; Marco Niosi; Mauro Valeriano D'Auria; Rita Capasso; Camillo Del Vecchio Blanco
Journal:  Dig Dis Sci       Date:  2007-04-05       Impact factor: 3.199

4.  Transcriptomic changes induced by acute ozone in resistant and sensitive Medicago truncatula accessions.

Authors:  Michael C Puckette; Yuhong Tang; Ramamurthy Mahalingam
Journal:  BMC Plant Biol       Date:  2008-04-23       Impact factor: 4.215

Review 5.  Dietary Flavonoids in the Prevention of T2D: An Overview.

Authors:  Hana Alkhalidy; Yao Wang; Dongmin Liu
Journal:  Nutrients       Date:  2018-03-31       Impact factor: 5.717

6.  Anti-hyperglycemic activity of myricetin, through inhibition of DPP-4 and enhanced GLP-1 levels, is attenuated by co-ingestion with lectin-rich protein.

Authors:  Nanjaiah Lalitha; Bettadahalli Sadashivaiah; Talahalli Ravichandra Ramaprasad; Sridevi Annapurna Singh
Journal:  PLoS One       Date:  2020-04-13       Impact factor: 3.240
  6 in total

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