| Literature DB >> 15494901 |
Jaya D Chidambaram1, Muluken Melese, Wondu Alemayehu, Elizabeth Yi, Tisha Prabriputaloong, David C Lee, Vicky Cevallos, Zhaoxia Zhou, John P Whitcher, Bruce D Gaynor, Thomas M Lietman.
Abstract
Azithromycin is highly effective against trachoma, but the practical difficulties of community-wide distribution often leave many individuals untreated. We demonstrate, after mass azithromycin treatment of a population in Ethiopia, an indirect protective effect that occurred among untreated children who resided in villages in which most individuals had been treated. Similarities with the indirect protection within a treated community (i.e., "herd protection") that has been observed in vaccination programs are discussed.Entities:
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Year: 2004 PMID: 15494901 DOI: 10.1086/424747
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079