Literature DB >> 1549463

Evolutionary conserved multiprotein complexes interact with the 3' untranslated region of histone transcripts.

R Eckner1, M L Birnstiel.   

Abstract

The replication dependent histone transcripts terminate with a highly conserved stem-loop structure. This feature distinguishes them from most other eukaryotic mRNAs which end with a poly(A) tail. The 3' terminus of histone mRNA is a main determinant for rapid turnover of these transcripts. In this study, we report the identification of two cytoplasmic protein complexes that interact in a sequence specific fashion with 3' terminal sequences of a mouse histone H4 and a human histone H2A mRNA. The binding activities are conserved from frog to man. At least a fraction of one of the protein complexes appears to be specifically associated with polysomes. The evidence for an involvement of the observed protein complexes in turnover of histone transcripts is discussed.

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Year:  1992        PMID： 1549463      PMCID： PMC312086          DOI： 10.1093/nar/20.5.1023

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  47 in total

Review 1.  The regulation of histone synthesis in the cell cycle.

Authors:  M A Osley
Journal:  Annu Rev Biochem       Date:  1991       Impact factor: 23.643

2.  The stem-loop structure at the 3' end of histone mRNA is necessary and sufficient for regulation of histone mRNA stability.

Authors:  N B Pandey; W F Marzluff
Journal:  Mol Cell Biol       Date:  1987-12       Impact factor: 4.272

3.  A stem-loop in the 3' untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm.

Authors:  E W Müllner; L C Kühn
Journal:  Cell       Date:  1988-06-03       Impact factor: 41.582

4.  Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3' AU-rich sequences.

Authors:  T Wilson; R Treisman
Journal:  Nature       Date:  1988-11-24       Impact factor: 49.962

5.  The primary structure and expression of four cloned human histone genes.

Authors:  R Zhong; R G Roeder; N Heintz
Journal:  Nucleic Acids Res       Date:  1983-11-11       Impact factor: 16.971

6.  Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis.

Authors:  H L Sive; N Heintz; R G Roeder
Journal:  Mol Cell Biol       Date:  1984-12       Impact factor: 4.272

7.  Histone mRNA concentrations are regulated at the level of transcription and mRNA degradation.

Authors:  D B Sittman; R A Graves; W F Marzluff
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

8.  An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

Authors:  G Brewer
Journal:  Mol Cell Biol       Date:  1991-05       Impact factor: 4.272

9.  Estrogen-induced destabilization of yolk precursor protein mRNAs in avian liver.

Authors:  D A Gordon; G S Shelness; M Nicosia; D L Williams
Journal:  J Biol Chem       Date:  1988-02-25       Impact factor: 5.157

10.  Different complexes are formed on the 3' end of histone mRNA with nuclear and polyribosomal proteins.

Authors:  N B Pandey; J H Sun; W F Marzluff
Journal:  Nucleic Acids Res       Date:  1991-10-25       Impact factor: 16.971
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  6 in total

1.  An Arabidopsis histone H2A mutant is deficient in Agrobacterium T-DNA integration.

Authors:  K S Mysore; J Nam; S B Gelvin
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-18       Impact factor: 11.205

2.  The histone 3'-terminal stem-loop is necessary for translation in Chinese hamster ovary cells.

Authors:  D R Gallie; N J Lewis; W F Marzluff
Journal:  Nucleic Acids Res       Date:  1996-05-15       Impact factor: 16.971

Review 3.  mRNA stability in mammalian cells.

Authors:  J Ross
Journal:  Microbiol Rev       Date:  1995-09

4.  The destabilizing elements in the coding region of c-fos mRNA are recognized as RNA.

Authors:  C L Wellington; M E Greenberg; J G Belasco
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

5.  Structure and dynamics of the DNA hairpins formed by tandemly repeated CTG triplets associated with myotonic dystrophy.

Authors:  S V Mariappan; A E Garcoa; G Gupta
Journal:  Nucleic Acids Res       Date:  1996-02-15       Impact factor: 16.971

6.  Global Analysis of the Human RNA Degradome Reveals Widespread Decapped and Endonucleolytic Cleaved Transcripts.

Authors:  Jung-Im Won; JaeMoon Shin; So Young Park; JeeHee Yoon; Dong-Hoon Jeong
Journal:  Int J Mol Sci       Date:  2020-09-04       Impact factor: 5.923
  6 in total

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