Literature DB >> 15493887

Monolayer-controlled substrate selectivity using noncovalent enzyme-nanoparticle conjugates.

Rui Hong1, Todd Emrick, Vincent M Rotello.   

Abstract

Electrostatic interactions were used to noncovalently conjugate chymotrypsin to gold nanoparticles featuring hybrid tetraethylene(glycol)alkanethiol monolayers terminated with carboxylate groups. This conjugation process greatly alters the substrate selectivity of the adsorbed chymotrypsin, inhibiting the hydrolysis of anionic subtrates without affecting the hydrolysis rate of cationic analogues.

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Year:  2004        PMID： 15493887     DOI： 10.1021/ja0461163

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  14 in total

1.  Noncovalent modification of chymotrypsin surface using an amphiphilic polymer scaffold: implications in modulating protein function.

Authors:  Britto S Sandanaraj; Dharma Rao Vutukuri; Joseph M Simard; Akamol Klaikherd; Rui Hong; Vincent M Rotello; S Thayumanavan
Journal:  J Am Chem Soc       Date:  2005-08-03       Impact factor: 15.419

2.  Inkjet-printed gold nanoparticle surfaces for the detection of low molecular weight biomolecules by laser desorption/ionization mass spectrometry.

Authors:  Alyssa L M Marsico; Brian Creran; Bradley Duncan; S Gokhan Elci; Ying Jiang; Timothy B Onasch; Joda Wormhoudt; Vincent M Rotello; Richard W Vachet
Journal:  J Am Soc Mass Spectrom       Date:  2015-07-23       Impact factor: 3.109

Review 3.  Beauty is skin deep: a surface monolayer perspective on nanoparticle interactions with cells and bio-macromolecules.

Authors:  Krishnendu Saha; Avinash Bajaj; Bradley Duncan; Vincent M Rotello
Journal:  Small       Date:  2011-06-14       Impact factor: 13.281

4.  Differential modulation of the active site environment of human carbonic anhydrase XII by cationic quantum dots and polylysine.

Authors:  Sumathra Manokaran; Xing Zhang; Wei Chen; D K Srivastava
Journal:  Biochim Biophys Acta       Date:  2010-03-06

5.  Surface properties dictate uptake, distribution, excretion, and toxicity of nanoparticles in fish.

Authors:  Zheng-Jiang Zhu; Rachel Carboni; Michael J Quercio; Bo Yan; Oscar R Miranda; Douglas L Anderton; Kathleen F Arcaro; Vincent M Rotello; Richard W Vachet
Journal:  Small       Date:  2010-10-18       Impact factor: 13.281

6.  Nano meets biology: structure and function at the nanoparticle interface.

Authors:  Daniel F Moyano; Vincent M Rotello
Journal:  Langmuir       Date:  2011-04-08       Impact factor: 3.882

7.  Quantitative imaging of 2 nm monolayer-protected gold nanoparticle distributions in tissues using laser ablation inductively-coupled plasma mass spectrometry (LA-ICP-MS).

Authors:  S Gokhan Elci; Bo Yan; Sung Tae Kim; Krishnendu Saha; Ying Jiang; Gunnar A Klemmer; Daniel F Moyano; Gulen Yesilbag Tonga; Vincent M Rotello; Richard W Vachet
Journal:  Analyst       Date:  2016-03-16       Impact factor: 4.616

8.  Environmentally responsive histidine-carboxylate zipper formation between proteins and nanoparticles.

Authors:  Rubul Mout; Gulen Yesilbag Tonga; Moumita Ray; Daniel F Moyano; Yuqing Xing; Vincent M Rotello
Journal:  Nanoscale       Date:  2014-08-07       Impact factor: 7.790

Review 9.  Assessing the range of enzymatic and oxidative tunability for biosensor design.

Authors:  Hattie C Schunk; Derek S Hernandez; Mariah J Austin; Kabir S Dhada; Adrianne M Rosales; Laura J Suggs
Journal:  J Mater Chem B       Date:  2020-04-29       Impact factor: 6.331

Review 10.  Regulation of enzyme activity through interactions with nanoparticles.

Authors:  Zhaochun Wu; Bin Zhang; Bing Yan
Journal:  Int J Mol Sci       Date:  2009-11-20       Impact factor: 6.208
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