| Literature DB >> 15489399 |
B A Racette1, G J Esper, J Antenor, K J Black, A Burkey, S M Moerlein, T O Videen, V Kotagal, J G Ojemann, J S Perlmutter.
Abstract
We report a patient with hydrocephalus who developed levodopa responsive parkinsonism and severe bradyphrenia associated with shunt malfunction and revision. Magnetic resonance imaging revealed periaqueductal edema involving medial substantia nigra. [18F]dopa positron emission tomography demonstrated reduced uptake in the caudate and putamen with relative sparing of the posterior putamen. Hydrocephalus associated with shunt malfunction can cause a distinct parkinsonian syndrome with greater dysfunction of projections from the medial substantia nigra to anterior striatum than in idiopathic Parkinson's disease.Entities:
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Year: 2004 PMID: 15489399 PMCID: PMC1738818 DOI: 10.1136/jnnp.2003.028449
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN: 0022-3050 Impact factor: 10.154