Literature DB >> 1548179

Mycinamicins, new macrolide antibiotics. XIII. Isolation and structures of novel fermentation products from Micromonospora griseorubida (FERM BP-705).

K Kinoshita1, S Takenaka, H Suzuki, T Morohoshi, M Hayashi.   

Abstract

Novel 16-membered macrolide antibiotics, mycinamicins IX, XII, XIII, XIV, XV, XVI, XVII and XVIII have been isolated from the culture filtrate of Micromonospora griseorubida (FERM BP-705). Fermentation, isolation, structure determination and biosynthetic consideration of these mycinamicin analogs are described.

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Year:  1992        PMID： 1548179     DOI： 10.7164/antibiotics.45.1

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

1.  Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics.

Authors:  Yojiro Anzai; Shengying Li; Mani Raj Chaulagain; Kenji Kinoshita; Fumio Kato; John Montgomery; David H Sherman
Journal:  Chem Biol       Date:  2008-09-22

Review 2.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

3.  Substrate recognition by the multifunctional cytochrome P450 MycG in mycinamicin hydroxylation and epoxidation reactions.

Authors:  Shengying Li; Drew R Tietz; Florentine U Rutaganira; Petrea M Kells; Yojiro Anzai; Fumio Kato; Thomas C Pochapsky; David H Sherman; Larissa M Podust
Journal:  J Biol Chem       Date:  2012-09-05       Impact factor: 5.157

4.  Solution Conformations and Dynamics of Substrate-Bound Cytochrome P450 MycG.

Authors:  Drew R Tietz; Larissa M Podust; David H Sherman; Thomas C Pochapsky
Journal:  Biochemistry       Date:  2017-05-16       Impact factor: 3.162

5.  Computational-Based Mechanistic Study and Engineering of Cytochrome P450 MycG for Selective Oxidation of 16-Membered Macrolide Antibiotics.

Authors:  Song Yang; Matthew D DeMars; Jessica M Grandner; Noelle M Olson; Yojiro Anzai; David H Sherman; K N Houk
Journal:  J Am Chem Soc       Date:  2020-10-08       Impact factor: 15.419

6.  Function of cytochrome P450 enzymes MycCI and MycG in Micromonospora griseorubida, a producer of the macrolide antibiotic mycinamicin.

Authors:  Yojiro Anzai; Shu-ichi Tsukada; Ayami Sakai; Ryohei Masuda; Chie Harada; Ayaka Domeki; Shengying Li; Kenji Kinoshita; David H Sherman; Fumio Kato
Journal:  Antimicrob Agents Chemother       Date:  2012-04-30       Impact factor: 5.191

Review 7.  The genus Micromonospora as a model microorganism for bioactive natural product discovery.

Authors:  Mohamed S Hifnawy; Mohamed M Fouda; Ahmed M Sayed; Rabab Mohammed; Hossam M Hassan; Sameh F AbouZid; Mostafa E Rateb; Alexander Keller; Martina Adamek; Nadine Ziemert; Usama Ramadan Abdelmohsen
Journal:  RSC Adv       Date:  2020-06-08       Impact factor: 4.036

8.  Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics.

Authors:  Shengying Li; Yojiro Anzai; Kenji Kinoshita; Fumio Kato; David H Sherman
Journal:  Chembiochem       Date:  2009-05-25       Impact factor: 3.164
  8 in total

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