| Literature DB >> 15472920 |
V Martino1, J Morales, J J Martínez-Irujo, M Font, A Monge, J Coussio.
Abstract
The bioassay- guided fractionation of the aqueous extract of Terminalia triflora leaves afforded punicalin and 2-O-galloylpunicalin, isolated for the first time from this species. These compounds showed inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner. Punicalin showed an IC(50) of 0.11 microg/ml (0.14 microM) and 2-O-galloylpunicalin an IC(50) of 0.10 microg/ml (0.11 microM). Copyright (c) 2004 John Wiley & Sons, Ltd.Entities:
Mesh:
Substances:
Year: 2004 PMID: 15472920 DOI: 10.1002/ptr.1504
Source DB: PubMed Journal: Phytother Res ISSN: 0951-418X Impact factor: 5.878