Literature DB >> 15470926

Integrating a MRI scanner with a 6 MV radiotherapy accelerator: dose deposition in a transverse magnetic field.

B W Raaymakers1, A J E Raaijmakers, A N T J Kotte, D Jette, J J W Lagendijk.   

Abstract

Integrating magnetic resonance imaging (MRI) functionality with a radiotherapy accelerator can facilitate on-line, soft-tissue based, position verification. A technical feasibility study, in collaboration with Elekta Oncology Systems and Philips Medical Systems, led to the preliminary design specifications of a MRI accelerator. Basically the design is a 6 MV accelerator rotating around a 1.5 T MRI system. Several technical issues and the clinical rational are currently under investigation. The aim of this paper is to determine the impact of the transverse 1.5 T magnetic field on the dose deposition. Monte Carlo simulations were used to calculate the dose deposition kernel in the presence of 1.5 T. This kernel in turn was used to determine the dose deposition for larger fields. Also simulations and measurements were done in the presence of 1.1 T. The pencil beam dose deposition is asymmetric. For larger fields the asymmetry persists but decreases. For the latter the distance to dose maximum is reduced by approximately 5 mm, the penumbra is increased by approximately 1 mm, and the 50% isodose line is shifted approximately 1 mm. The dose deposition in the presence of 1.5 T is affected, but the effect can be taken into account in a conventional treatment planning procedure. The impact of the altered dose deposition for clinical IMRT treatments is the topic of further research.

Mesh:

Year:  2004        PMID: 15470926     DOI: 10.1088/0031-9155/49/17/019

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  39 in total

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4.  Monte Carlo simulations of patient dose perturbations in rotational-type radiotherapy due to a transverse magnetic field: a tomotherapy investigation.

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Review 5.  MR-guided radiation therapy: transformative technology and its role in the central nervous system.

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Review 6.  The future of image-guided radiotherapy will be MR guided.

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Review 7.  Biological effects of static magnetic field exposure in the context of MR-guided radiotherapy.

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Journal:  Br J Radiol       Date:  2018-10-31       Impact factor: 3.039

8.  Relative dosimetry with an MR-linac: Response of ion chambers, diamond, and diode detectors for off-axis, depth dose, and output factor measurements.

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Journal:  Med Phys       Date:  2017-12-21       Impact factor: 4.071

Review 9.  Magnetic resonance imaging in precision radiation therapy for lung cancer.

Authors:  Hannah Bainbridge; Ahmed Salem; Rob H N Tijssen; Michael Dubec; Andreas Wetscherek; Corinne Van Es; Jose Belderbos; Corinne Faivre-Finn; Fiona McDonald
Journal:  Transl Lung Cancer Res       Date:  2017-12

10.  Technical Note: A Monte Carlo study of magnetic-field-induced radiation dose effects in mice.

Authors:  Ashley E Rubinstein; Zhongxing Liao; Adam D Melancon; Michele Guindani; David S Followill; Ramesh C Tailor; John D Hazle; Laurence E Court
Journal:  Med Phys       Date:  2015-09       Impact factor: 4.071

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