Literature DB >> 1546443

Immunologic and genetic characterization of S180, a cell line of murine origin capable of growing in different inbred strains of mice.

G Alfaro1, C Lomeli, R Ocadiz, V Ortega, R Barrera, M Ramirez, G Nava.   

Abstract

Some of the immunologic and genetic properties of the cell line S180 have been examined. These cells grew without restrictions in the peritoneal cavity of different inbred strains of mice and invariably killed the animals. With Northern blots it was demonstrated that S180 cells contained class I mRNAs but failed to transcribe B2m genes. However, under experimental conditions, a protective humoral immune response mediated by cytotoxic antibodies and complement against S180 cells was obtained through non-H-2 antigens in C57BL/6J mice.

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Year:  1992        PMID： 1546443     DOI： 10.1016/0165-2427(92)90107-2

Source DB:  PubMed          Journal:  Vet Immunol Immunopathol        ISSN： 0165-2427            Impact factor:   2.046


  8 in total

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7.  Immune cells from SR/CR mice induce the regression of established tumors in BALB/c and C57BL/6 mice.

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  8 in total

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