Literature DB >> 15463530

Onchocerca ochengi: Mimic, model or modulator of O. volvulus?

A J Trees1.   

Abstract

The cattle parasite, Onchocerca ochengi, is widely distributed in West Africa. Significantly, Simulium darnnosum, the vector o f the important human parasite, O. volvulus, the cause o f river blindness, also appears to be the vector of O. ochengi. For epidemiological reasons it is therefore vital to be able to distinguish the infective larvae o f these filoriae. Here, Sandy Trees also describes other features of the cattle parasite that make it of significance to investigations of human filariases.

Entities:  

Year:  1992        PMID: 15463530     DOI: 10.1016/0169-4758(92)90068-d

Source DB:  PubMed          Journal:  Parasitol Today        ISSN: 0169-4758


  14 in total

1.  Down-regulated lymphoproliferation coincides with parasite maturation and with the collapse of both gamma interferon and interleukin-4 responses in a bovine model of onchocerciasis.

Authors:  S P Graham; A J Trees; R A Collins; D M Moore; F M Guy; M J Taylor; A E Bianco
Journal:  Infect Immun       Date:  2001-07       Impact factor: 3.441

2.  Population biology of human onchocerciasis.

Authors:  M G Basáñez; M Boussinesq
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-04-29       Impact factor: 6.237

3.  Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent relationship.

Authors:  N G Langworthy; A Renz; U Mackenstedt; K Henkle-Dührsen; M B de Bronsvoort; V N Tanya; M J Donnelly; A J Trees
Journal:  Proc Biol Sci       Date:  2000-06-07       Impact factor: 5.349

4.  In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination.

Authors:  Virginia L Tchakouté; Simon P Graham; Siv Aina Jensen; Benjamin L Makepeace; Charles K Nfon; Leo M Njongmeta; Sara Lustigman; Peter A Enyong; Vincent N Tanya; Albert E Bianco; Alexander J Trees
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-03       Impact factor: 11.205

5.  Onchocerca armillata contains the endosymbiotic bacterium Wolbachia and elicits a limited inflammatory response.

Authors:  Joseph M Neary; Alexander J Trees; David D Ekale; Vincent N Tanya; Udo Hetzel; Benjamin L Makepeace
Journal:  Vet Parasitol       Date:  2010-09-17       Impact factor: 2.738

6.  Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle.

Authors:  Barend M deC Bronsvoort; Alfons Renz; Virginia Tchakouté; Vincent N Tanya; David Ekale; Alexander J Trees
Journal:  Filaria J       Date:  2005-08-08

7.  A simple isothermal DNA amplification method to screen black flies for Onchocerca volvulus infection.

Authors:  Andy Alhassan; Benjamin L Makepeace; Elwyn James LaCourse; Mike Y Osei-Atweneboana; Clotilde K S Carlow
Journal:  PLoS One       Date:  2014-10-09       Impact factor: 3.240

8.  Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis.

Authors:  Alistair C Darby; Stuart D Armstrong; Germanus S Bah; Gaganjot Kaur; Margaret A Hughes; Suzanne M Kay; Pia Koldkjær; Lucille Rainbow; Alan D Radford; Mark L Blaxter; Vincent N Tanya; Alexander J Trees; Richard Cordaux; Jonathan M Wastling; Benjamin L Makepeace
Journal:  Genome Res       Date:  2012-08-23       Impact factor: 9.043

9.  UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle.

Authors:  Barend M Dec Bronsvoort; Benjamin L Makepeace; Alfons Renz; Vincent N Tanya; Lawrence Fleckenstein; David Ekale; Alexander J Trees
Journal:  Parasit Vectors       Date:  2008-06-20       Impact factor: 3.876

10.  Development and validation of an Onchocerca ochengi microfilarial hamster model for onchocerciasis drug screens.

Authors:  Glory Enjong Mbah; Rene Bilingwe Ayiseh; Fidelis Cho-Ngwa
Journal:  BMC Infect Dis       Date:  2016-08-11       Impact factor: 3.090

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