Literature DB >> 15462024

Research ethics committees: differences and moral judgement.

Sarah J L Edwards1, Richard Ashcroft, Simon Kirchin.   

Abstract

Many people argue that disagreements and inconsistencies between Research Ethics Committees are morally problematic and there has been much effort to 'harmonise' their judgements. Some inconsistencies are bad because they are due to irrationality, or carelessness, or the operation of conflicting interests, an so should be reduced or removed. Other inconsistencies, we argue, are not bad and should be left or even encouraged. In this paper we examine three arguments to reject the view that we should strive for complete consistency between committees. The first argument is that differences in judgement are not necessarily incompatible with ideas of justice for patients who are potential participants of research reviewed by different committees. We call this 'the justice argument.' The second argument is that such committees do not have access to a single moral truth, to which their judgement is supposed to correspond. We call this the 'moral pluralism argument.' The third argument is that the process of ethics committee review is also morally relevant and not solely the outcome. We call this the 'due process argument.' While we fall short of establishing exactly how much variation and on what substantive issues would ethical permissible, we show that it is largely inevitable and that a certain amount of variation could be seen as a desirable part of the institution of medical research.

Entities:  

Keywords:  Analytical Approach; Biomedical and Behavioral Research

Mesh:

Year:  2004        PMID: 15462024     DOI: 10.1111/j.1467-8519.2004.00407.x

Source DB:  PubMed          Journal:  Bioethics        ISSN: 0269-9702            Impact factor:   1.898


  20 in total

1.  Impact of NCI-mandated scientific review on protocol development and content.

Authors:  Ning Ning; Jingsheng Yan; Xian-Jin Xie; David E Gerber
Journal:  J Natl Compr Canc Netw       Date:  2015-04       Impact factor: 11.908

Review 2.  Ethics, audit, and research: all shades of grey.

Authors:  Derick T Wade
Journal:  BMJ       Date:  2005-02-26

3.  Reforming research ethics committees.

Authors:  Richard E Ashcroft; Ainsley J Newson; Piers M W Benn
Journal:  BMJ       Date:  2005-09-17

4.  Research ethics committees in Europe: implementing the directive, respecting diversity.

Authors:  A Hedgecoe; F Carvalho; P Lobmayer; F Raka
Journal:  J Med Ethics       Date:  2006-08       Impact factor: 2.903

5.  Should research ethics committees be told how to think?

Authors:  G M Sayers
Journal:  J Med Ethics       Date:  2007-01       Impact factor: 2.903

6.  Consistency in decision making by research ethics committees: a controlled comparison.

Authors:  E Angell; A J Sutton; K Windridge; M Dixon-Woods
Journal:  J Med Ethics       Date:  2006-11       Impact factor: 2.903

Review 7.  Proportional ethical review and the identification of ethical issues.

Authors:  D Hunter
Journal:  J Med Ethics       Date:  2007-04       Impact factor: 2.903

8.  Is ethical expertise possible?

Authors:  Jukka Varelius
Journal:  Med Health Care Philos       Date:  2007-08-22

9.  Defining financial conflicts and managing research relationships: an analysis of university conflict of interest committee decisions.

Authors:  Elizabeth A Boyd; Lisa A Bero
Journal:  Sci Eng Ethics       Date:  2007-11-15       Impact factor: 3.525

10.  Empirical assessments of clinical ethics services: implications for clinical ethics committees.

Authors:  Laura Williamson
Journal:  Clin Ethics       Date:  2007-12-01
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