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Literature DB >> 15452694

[Tissue engineering of the urinary bladder].

G Ram-Liebig¹, O W Hakenberg, M P Wirth.

Abstract

In tissue engineering of the urinary bladder with autologous cell transplantation, high differentiation of the cells cultivated in vitro on biocompatible membranes is essential for the functionality of the tissue constructs after implantation. The terminal differentiation of superficial urothelial cells has a key role because of the barrier function of these cells against urine. The aim of this study was to determine optimized conditions for the creation of terminally differentiated urothelium to cover large membrane surfaces. This can bring us closer to the goal of using functioning tissue constructs in clinical trials.

Mesh：

Substances：

Year: 2004 PMID： 15452694 DOI： 10.1007/s00120-004-0690-7

Source DB: PubMed Journal: Urologe A ISSN： 0340-2592 Impact factor: 0.639

14 in total

1. Organ and species specificity in the stimulation of transitional epithelial cell growth by fibroblasts.

Authors: A Staack; T Alexander; P Merguerian; M K Terris
Journal: Eur Urol Date: 2001-04 Impact factor: 20.096

Review 2. Urologic tissue engineering with small-intestinal submucosa: potential clinical applications.

Authors: E Y Cheng; B P Kropp
Journal: World J Urol Date: 2000-02 Impact factor: 4.226

Review 3. Biomaterials in functional reconstruction.

Authors: F Desgrandchamps
Journal: Curr Opin Urol Date: 2000-05 Impact factor: 2.309

Review 4. Proliferating cells versus differentiated cells in tissue engineering.

Authors: Raimund Strehl; Karl Schumacher; Uwe de Vries; Will W Minuth
Journal: Tissue Eng Date: 2002-02

5. Augmentation cystoplasty using pedicled and de-epithelialized gastric patches in the mini-pig model.

Authors: P Frey; N Lutz; A L Leuba
Journal: J Urol Date: 1996-08 Impact factor: 7.450

6. Enterocystoplasty using modified pedicled, detubularized, de-epithelialized sigmoid patches in the mini-pig model.

Authors: N Lutz; P Frey
Journal: J Urol Date: 1995-08 Impact factor: 7.450

7. Reconstruction of the urinary bladder mucosa in three-dimensional collagen gel culture: fibroblast-extracellular matrix interactions on the differentiation of transitional epithelial cells.

Authors: C Fujiyama; Z Masaki; H Sugihara
Journal: J Urol Date: 1995-06 Impact factor: 7.450

[Tissue engineering of the urinary bladder].

1. Organ and species specificity in the stimulation of transitional epithelial cell growth by fibroblasts.

Review 2. Urologic tissue engineering with small-intestinal submucosa: potential clinical applications.

Review 3. Biomaterials in functional reconstruction.

Review 4. Proliferating cells versus differentiated cells in tissue engineering.

5. Augmentation cystoplasty using pedicled and de-epithelialized gastric patches in the mini-pig model.

6. Enterocystoplasty using modified pedicled, detubularized, de-epithelialized sigmoid patches in the mini-pig model.

7. Reconstruction of the urinary bladder mucosa in three-dimensional collagen gel culture: fibroblast-extracellular matrix interactions on the differentiation of transitional epithelial cells.

8. Bladder augmentation using allogenic bladder submucosa seeded with cells.

9. Role of mesenchymal-epithelial interactions in normal bladder development.

10. Transplanted acellular allograft dermal matrix. Potential as a template for the reconstruction of viable dermis.

1. [Reconstructive urology in transition. From its origin into the all too near future].