Literature DB >> 15452304

Bias in parental transmission of the HLA-DR3 allele in Sardinian multiple sclerosis.

M G Marrosu1, C Sardu, E Cocco, G Costa, M R Murru, C Mancosu, R Murru, M Lai, P Contu.   

Abstract

The authors analyzed the female: male (F:M) ratio according to the HLA-DRB1-DQB1 genotype in a cohort of multiple sclerosis (MS) patients from Sardinia, where the disease is associated with DR3 and DR4. In the whole cohort of 1,097 patients, F:M ratio was 2.24; however, it was 2.88 in DR3/DR3 and 2.52 in DR3/DRX (X#DR3 and DR4) individuals. Parental transmission of DR3 and DR4, assessed in a set of 565 case-parent triads, showed evidence of paternal inheritance of DR3 in affected women, thus explaining the excess of females in the DR3 category.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15452304     DOI： 10.1212/01.wnl.0000138493.04890.7c

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  8 in total

1.  A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms.

Authors:  Marcos M Miretti; Emily C Walsh; Xiayi Ke; Marcos Delgado; Mark Griffiths; Sarah Hunt; Jonathan Morrison; Pamela Whittaker; Eric S Lander; Lon R Cardon; David R Bentley; John D Rioux; Stephan Beck; Panos Deloukas
Journal:  Am J Hum Genet       Date:  2005-03-01       Impact factor: 11.025

Review 2.  Biomarkers in Multiple Sclerosis.

Authors:  Anu Paul; Manuel Comabella; Roopali Gandhi
Journal:  Cold Spring Harb Perspect Med       Date:  2019-03-01       Impact factor: 6.915

3.  Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes.

Authors:  P G Bronson; P P Ramsay; G Thomson; L F Barcellos
Journal:  Diabetes Obes Metab       Date:  2009-02       Impact factor: 6.577

4.  Parental transmission of HLA-DRB1*15 in multiple sclerosis.

Authors:  Sreeram V Ramagopalan; Blanca M Herrera; Jordana T Bell; David A Dyment; Gabriele C Deluca; Matthew R Lincoln; Sarah M Orton; Michael J Chao; A Dessa Sadovnick; George C Ebers
Journal:  Hum Genet       Date:  2007-10-31       Impact factor: 4.132

5.  Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.

Authors:  James A Traherne; Roger Horton; Anne N Roberts; Marcos M Miretti; Matthew E Hurles; C Andrew Stewart; Jennifer L Ashurst; Alexey M Atrazhev; Penny Coggill; Sophie Palmer; Jeff Almeida; Sarah Sims; Laurens G Wilming; Jane Rogers; Pieter J de Jong; Mary Carrington; John F Elliott; Stephen Sawcer; John A Todd; John Trowsdale; Stephan Beck
Journal:  PLoS Genet       Date:  2006-01-27       Impact factor: 5.917

Review 6.  A systematic review of the incidence and prevalence of comorbidity in multiple sclerosis: overview.

Authors:  Ruth Ann Marrie; Jeffrey Cohen; Olaf Stuve; Maria Trojano; Per Soelberg Sørensen; Stephen Reingold; Gary Cutter; Nadia Reider
Journal:  Mult Scler       Date:  2015-01-26       Impact factor: 6.312

7.  Biomarkers in Multiple Sclerosis: An Up-to-Date Overview.

Authors:  Serafeim Katsavos; Maria Anagnostouli
Journal:  Mult Scler Int       Date:  2013-01-22

8.  Variants of ST8SIA1 are associated with risk of developing multiple sclerosis.

Authors:  Seema Husain; Cagri Yildirim-Toruner; Justin P Rubio; Judith Field; Marvin Schwalb; Stuart Cook; Marcella Devoto; Emilia Vitale
Journal:  PLoS One       Date:  2008-07-09       Impact factor: 3.240
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.