Literature DB >> 15451319

Azaphilone pigments from a yellow mutant of the fungus Monascus kaoliang.

Suchada Jongrungruangchok1, Prasat Kittakoop, Busaba Yongsmith, Rapepol Bavovada, Somboon Tanasupawat, Nattapat Lartpornmatulee, Yodhathai Thebtaranonth.   

Abstract

Azaphilone pigments, monascusones A (1) and B (2), together with two known azaphilones, monascin (3) and FK17-P2b2 (4), were isolated from the CH2Cl2 extract of a yellow mutant of the fungus M. kaoliang grown on rice. Structures of the isolated compounds were elucidated by analyses of spectroscopic data. Monascusone A (1), the major metabolite of M. kaoliang, showed no antimalarial (against Plasmodium falciparum), antitubercular (against Mycobacterium tuberculosis H37Ra), and antifungal (toward Candida albicans) activities. Compound 1 exhibited no cytotoxicity against BC (breast cancer) and KB (human epidermoid carcinoma of cavity) cell lines.

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Year:  2004        PMID： 15451319     DOI： 10.1016/j.phytochem.2004.08.032

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  9 in total

Review 1.  Production and biological activities of yellow pigments from Monascus fungi.

Authors:  Gong Chen; Zhenqiang Wu
Journal:  World J Microbiol Biotechnol       Date:  2016-06-29       Impact factor: 3.312

2.  Monascus pigment rubropunctatin derivative FZU-H reduces Aβ(1-42)-induced neurotoxicity in Neuro-2A cells.

Authors:  Yunquan Zheng; Qisheng Pan; Liuda Mo; Wenyi Zhang; Yunjian Duan; Chengqun Chen; Haijun Chen; Yanghao Guo; Xianai Shi; Jianmin Yang
Journal:  RSC Adv       Date:  2018-05-14       Impact factor: 4.036

Review 3.  Nature and nurture: confluence of pathway determinism with metabolic and chemical serendipity diversifies Monascus azaphilone pigments.

Authors:  Wanping Chen; Yanli Feng; István Molnár; Fusheng Chen
Journal:  Nat Prod Rep       Date:  2019-04-17       Impact factor: 13.423

Review 4.  Monascus secondary metabolites: production and biological activity.

Authors:  Petra Patakova
Journal:  J Ind Microbiol Biotechnol       Date:  2012-11-20       Impact factor: 3.346

Review 5.  Beneficial Effects of Monascus sp. KCCM 10093 Pigments and Derivatives: A Mini Review.

Authors:  Daehwan Kim; Seockmo Ku
Journal:  Molecules       Date:  2018-01-03       Impact factor: 4.411

6.  Monasnicotinates A-D, four new pyridine alkaloids from the fungal strain Monascus pilosus BCRC 38093.

Authors:  Ming-Der Wu; Ming-Jen Cheng; Yi-Jen Yech; Yen-Lin Chen; Kai-Ping Chen; Ih-Sheng Chen; Ping-Hsun Yang; Gwo-Fang Yuan
Journal:  Molecules       Date:  2011-06-07       Impact factor: 4.411

7.  Bioactive Metabolites from the Mariana Trench Sediment-Derived Fungus Penicillium sp. SY2107.

Authors:  Sidra Kaleem; Le Qin; Wenwen Yi; Xiao-Yuan Lian; Zhizhen Zhang
Journal:  Mar Drugs       Date:  2020-05-14       Impact factor: 5.118

8.  In vivo evaluation of the anti-obesity effects of combinations of Monascus pigment derivatives.

Authors:  Deokyeong Choe; Hyun Ho Jung; Daehwan Kim; Chul Soo Shin; Tony Vaughn Johnston; Seockmo Ku
Journal:  RSC Adv       Date:  2020-01-08       Impact factor: 4.036

9.  Increased Water-Soluble Yellow Monascus Pigment Productivity via Dual Mutagenesis and Submerged Repeated-Batch Fermentation of Monascus purpureus.

Authors:  Jie Bai; Zihan Gong; Meng Shu; Hui Zhao; Fanyu Ye; Chenglun Tang; Song Zhang; Bo Zhou; Dong Lu; Xiang Zhou; Qinlu Lin; Jun Liu
Journal:  Front Microbiol       Date:  2022-06-09       Impact factor: 6.064
  9 in total

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