Literature DB >> 15450501

The role of analytical sciences in medical systems biology.

Jan van der Greef1, Paul Stroobant, Rob van der Heijden.   

Abstract

Medical systems biology has generated widespread interest because of its bold conception and exciting potential, but the field is still in its infancy. Although there has been tremendous progress achieved recently in generating, integrating and analysing data in the medical and pharmaceutical field, many challenges remain, especially with respect to the crucial core technologies required for analytical characterization. This review briefly summarizes these aspects for metabolomics, proteomics, data handling and multivariate biostatistics.

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Year:  2004        PMID: 15450501     DOI: 10.1016/j.cbpa.2004.08.013

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  41 in total

Review 1.  New hyphenated methodologies in high-sensitivity glycoprotein analysis.

Authors:  Milos V Novotny; Yehia Mechref
Journal:  J Sep Sci       Date:  2005-10       Impact factor: 3.645

2.  Diagnosing diabetic nephropathy by 1H NMR metabonomics of serum.

Authors:  Ville-Petteri Mäkinen; Pasi Soininen; Carol Forsblom; Maija Parkkonen; Petri Ingman; Kimmo Kaski; Per-Henrik Groop; Mika Ala-Korpela
Journal:  MAGMA       Date:  2006-12-15       Impact factor: 2.310

3.  Elution-extrusion countercurrent chromatography: theory and concepts in metabolic analysis.

Authors:  Alain Berthod; J Brent Friesen; Taichi Inui; Guido F Pauli
Journal:  Anal Chem       Date:  2007-04-05       Impact factor: 6.986

4.  Metabolomic analysis and signatures in motor neuron disease.

Authors:  Steve Rozen; Merit E Cudkowicz; Mikhail Bogdanov; Wayne R Matson; Bruce S Kristal; Chris Beecher; Scott Harrison; Paul Vouros; Jimmy Flarakos; Karen Vigneau-Callahan; Theodore D Matson; Kristyn M Newhall; M Flint Beal; Robert H Brown; Rima Kaddurah-Daouk
Journal:  Metabolomics       Date:  2005       Impact factor: 4.290

Review 5.  Biochemical individuality reflected in chromatographic, electrophoretic and mass-spectrometric profiles.

Authors:  Milos V Novotny; Helena A Soini; Yehia Mechref
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-04-15       Impact factor: 3.205

6.  An optimal protocol to analyze the rat spinal cord proteome.

Authors:  F Gil-Dones; S Alonso-Orgaz; G Avila; T Martin-Rojas; V Moral-Darde; G Barroso; F Vivanco; J Scott-Taylor; M G Barderas
Journal:  Biomark Insights       Date:  2009-10-28

Review 7.  The emerging role of metabolomics in the development of biomarkers for pulmonary hypertension and other cardiovascular diseases (2013 Grover Conference series).

Authors:  Gregory D Lewis
Journal:  Pulm Circ       Date:  2014-09       Impact factor: 3.017

Review 8.  Clinical applications of metabolomics in oncology: a review.

Authors:  Jennifer L Spratlin; Natalie J Serkova; S Gail Eckhardt
Journal:  Clin Cancer Res       Date:  2009-01-15       Impact factor: 12.531

9.  Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits.

Authors:  Xinjie Zhao; Jens Fritsche; Jiangshan Wang; Jing Chen; Kilian Rittig; Philippe Schmitt-Kopplin; Andreas Fritsche; Hans-Ulrich Häring; Erwin D Schleicher; Guowang Xu; Rainer Lehmann
Journal:  Metabolomics       Date:  2010-03-07       Impact factor: 4.290

Review 10.  Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease.

Authors:  Joanna L Richens; Richard A Urbanowicz; Elizabeth A M Lunt; Rebecca Metcalf; Jonathan Corne; Lucy Fairclough; Paul O'Shea
Journal:  Respir Res       Date:  2009-04-22
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