Literature DB >> 15449333

Joint modelling of multivariate longitudinal profiles: pitfalls of the random-effects approach.

Steffen Fieuws1, Geert Verbeke.   

Abstract

Due to its flexibility, the random-effects approach for the joint modelling of multivariate longitudinal profiles received a lot of attention in recent publications. In this approach different mixed models are joined by specifying a common distribution for their random-effects. Parameter estimates of this common distribution can then be used to evaluate the relation between the different responses. Using bivariate longitudinal measurements on pure-tone hearing thresholds, it will be shown that such a random-effects approach can yield misleading results for evaluating this relationship. Copyright 2004 John Wiley & Sons, Ltd.

Mesh：

Year:  2004        PMID： 15449333     DOI： 10.1002/sim.1885

Source DB:  PubMed          Journal:  Stat Med        ISSN： 0277-6715            Impact factor:   2.373


  28 in total

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