Literature DB >> 15446852

Unprecedented acceleration of zirconium(IV)-assisted peptide hydrolysis at neutral pH.

Miki Kassai1, R Gnana Ravi, Sarah J Shealy, Kathryn B Grant.   

Abstract

4,13-Diaza-18-crown-6 substantially increases the rate of zirconium(IV) hydrolysis of unactivated peptide amide bonds under near-physiological conditions of temperature and pH. In the presence of this azacrown ether, ZrCl(4) efficiently hydrolyses both neutral and negatively charged peptides (pH 7.0-7.3, 37-60 degrees C).

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Year:  2004        PMID: 15446852     DOI: 10.1021/ic049433j

Source DB:  PubMed          Journal:  Inorg Chem        ISSN: 0020-1669            Impact factor:   5.165


  4 in total

1.  Soluble artificial metalloproteases with broad substrate selectivity, high reactivity, and high thermal and chemical stabilities.

Authors:  Min Gyum Kim; Sang Ho Yoo; Woo Suk Chei; Tae Yeon Lee; Hye Mi Kim; Junghun Suh
Journal:  J Biol Inorg Chem       Date:  2010-04-28       Impact factor: 3.358

2.  MOFzyme: Intrinsic protease-like activity of Cu-MOF.

Authors:  Bin Li; Daomei Chen; Jiaqiang Wang; Zhiying Yan; Liang Jiang; Jiao He; Zhongrui Luo; Jinping Zhang; Fagui Yuan
Journal:  Sci Rep       Date:  2014-10-24       Impact factor: 4.379

3.  Hydrolysis of Methionine- and Histidine-Containing Peptides Promoted by Dinuclear Platinum(II) Complexes with Benzodiazines as Bridging Ligands: Influence of Ligand Structure on the Catalytic Ability of Platinum(II) Complexes.

Authors:  Snežana Rajković; Beata Warżajtis; Marija D Živković; Biljana Đ Glišić; Urszula Rychlewska; Miloš I Djuran
Journal:  Bioinorg Chem Appl       Date:  2018-05-08       Impact factor: 7.778

Review 4.  Amide Bond Activation of Biological Molecules.

Authors:  Sriram Mahesh; Kuei-Chien Tang; Monika Raj
Journal:  Molecules       Date:  2018-10-12       Impact factor: 4.411

  4 in total

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