Literature DB >> 1543912

New gene in the homologous human 11q13-q14 and mouse 7F chromosomal regions.

V Ollendorff1, P Szepetowski, M G Mattei, P Gaudray, D Birnbaum.   

Abstract

Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies in which most of the key genes remain to be identified. In an effort to isolate as many candidates as possible, we are cloning genes from this region. We report here the mapping of a new sequence from 11q13.5-11q14. This sequence, designated D11S833E, putatively encodes a new gene, provisionally named GARP. We cloned its homologous sequence in the mouse and located it on Chromosome (Chr) 7, region F. The human and mouse genes belong to a conserved group of synteny. This, together with the similar conservation of the FGF and TYR genes, indicates that the human 11q13-q14 and mouse 7E-7F regions share homology.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1543912     DOI： 10.1007/bf00302877

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  38 in total

1.  The 11q13 amplicon of a mammary carcinoma cell line.

Authors:  M Lafage; C Nguyen; P Szepetowski; M J Pébusque; J Simonetti; G Courtois; P Gaudray; O deLapeyriere; B Jordan; D Birnbaum
Journal:  Genes Chromosomes Cancer       Date:  1990-09       Impact factor: 5.006

2.  Rare McArdle disease locus polymorphic site on 11q13 contains CpG sequence.

Authors:  R V Lebo; L A Anderson; S DiMauro; E Lynch; P Hwang; R Fletterick
Journal:  Hum Genet       Date:  1990-11       Impact factor: 4.132

3.  Frequent rearrangement of chromosomal bands 1p22 and 11q13 in squamous cell carcinomas of the head and neck.

Authors:  Y S Jin; K Higashi; N Mandahl; S Heim; J Wennerberg; A Biörklund; M Dictor; F Mitelman
Journal:  Genes Chromosomes Cancer       Date:  1990-09       Impact factor: 5.006

4.  D11S146 and BCL1 are physically linked but can be discriminated by their amplification status in human breast cancer.

Authors:  P Szepetowski; C Nguyen; D Perucca-Lostanlen; G F Carle; Y Tsujimoto; D Birnbaum; C Theillet; P Gaudray
Journal:  Genomics       Date:  1991-06       Impact factor: 5.736

5.  Amplification of the int-2 gene in human head and neck squamous cell carcinomas.

Authors:  K D Somers; S L Cartwright; G L Schechter
Journal:  Oncogene       Date:  1990-06       Impact factor: 9.867

6.  Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors.

Authors:  C L Rosenberg; H G Kim; T B Shows; H M Kronenberg; A Arnold
Journal:  Oncogene       Date:  1991-03       Impact factor: 9.867

7.  Frequent amplification of the bcl-1 locus in poorly differentiated squamous cell carcinoma of the lung. The Lung Cancer Study Group.

Authors:  J R Berenson; H Koga; J Yang; J Pearl; E C Holmes; R Figlin
Journal:  Oncogene       Date:  1990-09       Impact factor: 9.867

8.  Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation.

Authors:  Y Tsujimoto; E Jaffe; J Cossman; J Gorham; P C Nowell; C M Croce
Journal:  Nature       Date:  1985 May 23-29       Impact factor: 49.962

9.  Regional assignment of genes for human alpha-globin and phosphoglycollate phosphatase to the short arm of chromosome 16.

Authors:  H P Koeffler; R S Sparkes; H Stang; T Mohandas
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

10.  Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.

Authors:  C Byström; C Larsson; C Blomberg; K Sandelin; U Falkmer; B Skogseid; K Oberg; S Werner; M Nordenskjöld
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205
View more
  12 in total

1.  CD4+  CD25+  GARP+ regulatory T cells display a compromised suppressive function in patients with dilated cardiomyopathy.

Authors:  Yuzhen Wei; Kunwu Yu; Hui Wei; Xin Su; Ruirui Zhu; Huairui Shi; Haitao Sun; Quan Luo; Wenbin Xu; Junhui Xiao; Yucheng Zhong; Qiutang Zeng
Journal:  Immunology       Date:  2017-03-29       Impact factor: 7.397

2.  GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells.

Authors:  Dat Q Tran; John Andersson; Rui Wang; Heather Ramsey; Derya Unutmaz; Ethan M Shevach
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-27       Impact factor: 11.205

3.  B lymphocytes confer immune tolerance via cell surface GARP-TGF-β complex.

Authors:  Caroline H Wallace; Bill X Wu; Mohammad Salem; Ephraim A Ansa-Addo; Alessandra Metelli; Shaoli Sun; Gary Gilkeson; Mark J Shlomchik; Bei Liu; Zihai Li
Journal:  JCI Insight       Date:  2018-04-05

4.  Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32).

Authors:  Derek V Chan; Ally-Khan Somani; Andrew B Young; Jessica V Massari; Jennifer Ohtola; Hideaki Sugiyama; Edina Garaczi; Denise Babineau; Kevin D Cooper; Thomas S McCormick
Journal:  BMC Biochem       Date:  2011-05-26       Impact factor: 4.059

5.  ZNF703 gene amplification at 8p12 specifies luminal B breast cancer.

Authors:  Fabrice Sircoulomb; Nathalie Nicolas; Anthony Ferrari; Pascal Finetti; Ismahane Bekhouche; Estelle Rousselet; Aurélie Lonigro; José Adélaïde; Emilie Baudelet; Séverine Esteyriès; Julien Wicinski; Stéphane Audebert; Emmanuelle Charafe-Jauffret; Jocelyne Jacquemier; Marc Lopez; Jean-Paul Borg; Christos Sotiriou; Cornel Popovici; François Bertucci; Daniel Birnbaum; Max Chaffanet; Christophe Ginestier
Journal:  EMBO Mol Med       Date:  2011-02-15       Impact factor: 12.137

6.  The role of platelet and endothelial GARP in thrombosis and hemostasis.

Authors:  Elien Vermeersch; Frederik Denorme; Wim Maes; Simon F De Meyer; Karen Vanhoorelbeke; Justin Edwards; Ethan M Shevach; Derya Unutmaz; Hodaka Fujii; Hans Deckmyn; Claudia Tersteeg
Journal:  PLoS One       Date:  2017-03-09       Impact factor: 3.240

7.  Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.

Authors:  J Adélaide; G Monges; C Dérdérian; J F Seitz; D Birnbaum
Journal:  Br J Cancer       Date:  1995-01       Impact factor: 7.640

8.  Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression.

Authors:  Rui Wang; Qi Wan; Lina Kozhaya; Hodaka Fujii; Derya Unutmaz
Journal:  PLoS One       Date:  2008-07-16       Impact factor: 3.240

Review 9.  GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-β releasing.

Authors:  Liping Sun; Hao Jin; Hui Li
Journal:  Oncotarget       Date:  2016-07-05

Review 10.  Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer.

Authors:  Alessandra Metelli; Mohammad Salem; Caroline H Wallace; Bill X Wu; Anqi Li; Xue Li; Zihai Li
Journal:  J Hematol Oncol       Date:  2018-02-20       Impact factor: 17.388
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.