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Literature DB >> 1541536

Chlamydia trachomatis pneumonia induces in vivo production of interleukin-1 and -6.

D M Magee¹, J G Smith, C A Bleicker, C J Carter, L F Bonewald, J Schachter, D M Williams.

Abstract

Cytokine induction during Chlamydia trachomatis pneumonia may alter the pathogenesis or course of disease. We examined interleukin-1 (IL-1) and IL-6 production by measuring mRNA and bioactivity in murine lungs. mRNA and bioactivity for IL-1 alpha, IL-1 beta, and IL-6 increased after Chlamydia infection. These cytokines may be important in regulating host defenses against C. trachomatis.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1992 PMID： 1541536 PMCID： PMC257615 DOI： 10.1128/iai.60.3.1217-1220.1992

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

32 in total

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