A Ramel1, K-H Wagner, I Elmadfa. 1. Unit for Nutrition Research, University of Iceland, Reykjavik, Iceland. ramel@hi.is <ramel@hi.is>
Abstract
BACKGROUND: Generation of reactive oxygen species (ROS) during exercise has been linked to increased oxygen consumption. ROS could also be produced by other mechanisms-for example, a respiratory burst of neutrophils or catecholamine auto-oxidation-when oxygen consumption is only moderately increased. OBJECTIVES: To investigate noradrenaline concentrations, neutrophil counts, plasma antioxidants, and lipid oxidation products before and after acute resistance exercise. METHODS: 17 male participants undertook a submaximal resistance exercise circuit (10 exercises; 75% of the one repetition maximum; mean (SD) exercise time, 18.6 (1.1) minutes). Blood samples were taken before and immediately after exercise and analysed for plasma antioxidants, noradrenaline, neutrophils, and lipid oxidation products. Wilcoxon's signed-rank test and Pearson's correlation coefficient were used for calculations. RESULTS: Neutrophils, noradrenaline, fat soluble antioxidants, and lipid oxidation products increased after exercise. Noradrenaline concentrations were associated with higher antioxidant concentrations. Neutrophils were related to higher concentrations of conjugated dienes. CONCLUSIONS: Submaximal resistance exercise increases plasma antioxidants. This might reflect enhanced antioxidant defence in response to the oxidative stress of exercise, though this is not efficient for inhibiting lipid oxidation. The correlation between noradrenaline concentrations and plasma antioxidants suggests a modulating role of the stress hormone. Neutrophils are a possible source of oxidative stress after resistance exercise.
BACKGROUND: Generation of reactive oxygen species (ROS) during exercise has been linked to increased oxygen consumption. ROS could also be produced by other mechanisms-for example, a respiratory burst of neutrophils or catecholamine auto-oxidation-when oxygen consumption is only moderately increased. OBJECTIVES: To investigate noradrenaline concentrations, neutrophil counts, plasma antioxidants, and lipid oxidation products before and after acute resistance exercise. METHODS: 17 male participants undertook a submaximal resistance exercise circuit (10 exercises; 75% of the one repetition maximum; mean (SD) exercise time, 18.6 (1.1) minutes). Blood samples were taken before and immediately after exercise and analysed for plasma antioxidants, noradrenaline, neutrophils, and lipid oxidation products. Wilcoxon's signed-rank test and Pearson's correlation coefficient were used for calculations. RESULTS: Neutrophils, noradrenaline, fat soluble antioxidants, and lipid oxidation products increased after exercise. Noradrenaline concentrations were associated with higher antioxidant concentrations. Neutrophils were related to higher concentrations of conjugated dienes. CONCLUSIONS: Submaximal resistance exercise increases plasma antioxidants. This might reflect enhanced antioxidant defence in response to the oxidative stress of exercise, though this is not efficient for inhibiting lipid oxidation. The correlation between noradrenaline concentrations and plasma antioxidants suggests a modulating role of the stress hormone. Neutrophils are a possible source of oxidative stress after resistance exercise.
Authors: Johanna Ihalainen; Simon Walker; Gøran Paulsen; Keijo Häkkinen; William J Kraemer; Mari Hämäläinen; Katriina Vuolteenaho; Eeva Moilanen; Antti A Mero Journal: Eur J Appl Physiol Date: 2014-08-22 Impact factor: 3.078
Authors: Lucieli T Cambri; Gustavo G de Araujo; Ana C Ghezzi; José D Botezelli; Maria A R Mello Journal: Lipids Health Dis Date: 2011-09-21 Impact factor: 3.876