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Literature DB >> 15388479

Novel resistance-nodulation-cell division efflux system AdeDE in Acinetobacter genomic DNA group 3.

Sze-Lok Chau¹, Yiu-Wai Chu, Elizabeth T S Houang.

Abstract

Resistance-nodulation-cell division type efflux pump AdeDE was identified in acinetobacters belonging to genomic DNA group 3. Inactivation of adeE showed that it may be responsible for reduced susceptibility to amikacin, ceftazidime, chloramphenicol, ciprofloxacin, erythromycin, ethidium bromide, meropenem, rifampin, and tetracycline. However, unlike what was found for other similar efflux systems, the open reading frame for the outer membrane component was not found downstream of the adeDE gene cluster.

Entities: Chemical

Mesh：

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Year: 2004 PMID： 15388479 PMCID： PMC521926 DOI： 10.1128/AAC.48.10.4054-4055.2004

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

6 in total

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2. Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454.

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Journal: Antimicrob Agents Chemother Date: 2001-12 Impact factor: 5.191

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Journal: Clin Microbiol Rev Date: 1996-04 Impact factor: 26.132

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Journal: Scand J Infect Dis Suppl Date: 1996

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Authors: T Mine; Y Morita; A Kataoka; T Mizushima; T Tsuchiya
Journal: Antimicrob Agents Chemother Date: 1999-02 Impact factor: 5.191

6. Contribution of outer membrane efflux protein OprM to antibiotic resistance in Pseudomonas aeruginosa independent of MexAB.

Authors: Q Zhao; X Z Li; R Srikumar; K Poole
Journal: Antimicrob Agents Chemother Date: 1998-07 Impact factor: 5.191

6 in total

23 in total

Review 1. Efflux-mediated drug resistance in bacteria: an update.

Authors: Xian-Zhi Li; Hiroshi Nikaido
Journal: Drugs Date: 2009-08-20 Impact factor: 9.546

2. Antibiotic resistance and expression of resistance-nodulation-division pump- and outer membrane porin-encoding genes in Acinetobacter species isolated from Canadian hospitals.

Authors: Dinesh Fernando; George Zhanel; Ayush Kumar
Journal: Can J Infect Dis Med Microbiol Date: 2013 Impact factor: 2.471

Novel resistance-nodulation-cell division efflux system AdeDE in Acinetobacter genomic DNA group 3.

Review 1. Molecular properties of bacterial multidrug transporters.

2. Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454.

Review 3. Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features.

4. A retrospective study of clinical characteristics of acinetobacter bacteremia.

5. Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa.

6. Contribution of outer membrane efflux protein OprM to antibiotic resistance in Pseudomonas aeruginosa independent of MexAB.

Review 1. Efflux-mediated drug resistance in bacteria: an update.

2. Antibiotic resistance and expression of resistance-nodulation-division pump- and outer membrane porin-encoding genes in Acinetobacter species isolated from Canadian hospitals.

3. Functional Characterization of AbaQ, a Novel Efflux Pump Mediating Quinolone Resistance in Acinetobacter baumannii.

Review 4. Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria.

Review 5. Tetracycline Antibiotics and Resistance.

Review 6. Efflux-mediated antibiotic resistance in Acinetobacter spp.

7. First identification and characterization of an AdeABC-like efflux pump in Acinetobacter genomospecies 13TU.

8. Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria.

Review 9. Multidrug Resistant Acinetobacter baumannii: Resistance by Any Other Name Would Still be Hard to Treat.

Review 10. Acinetobacter baumannii: emergence of a successful pathogen.