Literature DB >> 15387718

Cancer prevention and therapeutics: Panax ginseng.

Steve Helms1.   

Abstract

Panax ginseng has been used as a medicinal plant in China for thousands of years. Current use in Western countries has been diverse, with focused research on cancer therapeutics. P. ginseng apparently mitigates cancer through anti-inflammatory, antioxidant, and apoptotic mechanisms to influence gene expression. Additional mechanisms of investigation include influence on neurotransmission and immunosurveillance. Low toxicity and positive studies in concomitant use with other chemotherapeutic agents is promising. Although there is no conclusive evidence of P. ginseng curing cancer, research has continually found tumor inhibition, especially in the promotion and progression phases.

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Year:  2004        PMID: 15387718

Source DB:  PubMed          Journal:  Altern Med Rev        ISSN: 1089-5159


  101 in total

1.  Synthesis of protopanaxadiol derivatives and evaluation of their anticancer activities.

Authors:  Guang-Jian Du; Qing Dai; Stainley Williams; Chong-Zhi Wang; Chun-Su Yuan
Journal:  Anticancer Drugs       Date:  2011-01       Impact factor: 2.248

2.  Use of complementary and alternative medicine by patients with cancer.

Authors:  Carmen L Watkins; Carlos Fernandez-Robles; Kathleen M Miller; Alexander Pine; Theodore A Stern
Journal:  Prim Care Companion CNS Disord       Date:  2011

Review 3.  Role of phytochemicals in colorectal cancer prevention.

Authors:  Yu-Hua Li; Yin-Bo Niu; Yang Sun; Feng Zhang; Chang-Xu Liu; Lei Fan; Qi-Bing Mei
Journal:  World J Gastroenterol       Date:  2015-08-21       Impact factor: 5.742

4.  Anti-Inflammatory Agents for Cancer Therapy.

Authors:  Elizabeth R Rayburn; Scharri J Ezell; Ruiwen Zhang
Journal:  Mol Cell Pharmacol       Date:  2009

5.  Ginsenoside Re: Its chemistry, metabolism and pharmacokinetics.

Authors:  Dacheng Peng; Huashan Wang; Chenling Qu; Laihua Xie; Sheila M Wicks; Jingtian Xie
Journal:  Chin Med       Date:  2012-02-07       Impact factor: 5.455

6.  Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen beta receptor.

Authors:  K W Leung; L W T Cheung; Y L Pon; R N S Wong; N K Mak; T-P D Fan; S C L Au; J Tombran-Tink; A S T Wong
Journal:  Br J Pharmacol       Date:  2007-07-02       Impact factor: 8.739

7.  Notoginsenoside R1 reduces blood pressure in spontaneously hypertensive rats through a long non-coding RNA AK094457.

Authors:  Ying Yang; Peng Xi; Yuan Xie; Cuimei Zhao; Jiahong Xu; Jinfa Jiang
Journal:  Int J Clin Exp Pathol       Date:  2015-03-01

8.  (3R, 9R, 10R)-Panaxytriol: A molecular-based nutraceutical with possible application to cancer prevention and treatment.

Authors:  Fay Ng; Heedong Yun; Xiaoguang Lei; Samuel J Danishefsky; Jed Fahey; Katherine Stephenson; Charles Flexner; Lawrence Lee
Journal:  Tetrahedron Lett       Date:  2008-12-08       Impact factor: 2.415

9.  Ginsenoside Rb1 Enhances Keratinocyte Migration by a Sphingosine-1-Phosphate-Dependent Mechanism.

Authors:  Kyong-Oh Shin; Sung Jay Choe; Yoshikazu Uchida; Inyong Kim; Yoonhwa Jeong; Kyungho Park
Journal:  J Med Food       Date:  2018-08-27       Impact factor: 2.786

Review 10.  Ginseng compounds: an update on their molecular mechanisms and medical applications.

Authors:  Jian-Ming Lü; Qizhi Yao; Changyi Chen
Journal:  Curr Vasc Pharmacol       Date:  2009-07       Impact factor: 2.719

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