Literature DB >> 15387660

07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived Xylariaceous fungus LL-07H239.

Leonard A McDonald1, Laurel R Barbieri, Valerie S Bernan, Jeffrey Janso, Peter Lassota, Guy T Carter.   

Abstract

07H239-A (1), a new eremophilane sesquiterpene from a marine-derived xylariaceous fungus, was isolated, characterized, and shown to be cytotoxic toward a variety of cancer cell lines, with some selectivity for a CCRFCEM leukemia line (IC(50) = 0.9 microg/mL).

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Year:  2004        PMID: 15387660     DOI: 10.1021/np049924g

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  12 in total

1.  Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.

Authors:  Robert R Lavieri; Sarah A Scott; Paige E Selvy; Kwangho Kim; Satyawan Jadhav; Ryan D Morrison; J Scott Daniels; H Alex Brown; Craig W Lindsley
Journal:  J Med Chem       Date:  2010-09-23       Impact factor: 7.446

Review 2.  Phospholipase D: enzymology, functionality, and chemical modulation.

Authors:  Paige E Selvy; Robert R Lavieri; Craig W Lindsley; H Alex Brown
Journal:  Chem Rev       Date:  2011-09-22       Impact factor: 60.622

Review 3.  Chemical modulation of glycerolipid signaling and metabolic pathways.

Authors:  Sarah A Scott; Thomas P Mathews; Pavlina T Ivanova; Craig W Lindsley; H Alex Brown
Journal:  Biochim Biophys Acta       Date:  2014-01-15

4.  A new eremophilane sesquiterpene from the fungus Xylaria sp. V-27 and inhibition activity against degranulation in RBL-2H3 cells.

Authors:  Abdou Tchoukoua; Takuma Suzuki; Nanang Rudianto Ariefta; Takuya Koseki; Yusuke Okawa; Ken-Ichi Kimura; Yoshihito Shiono
Journal:  J Antibiot (Tokyo)       Date:  2017-10-25       Impact factor: 2.649

5.  Cryptosphaerolide, a cytotoxic Mcl-1 inhibitor from a marine-derived ascomycete related to the genus Cryptosphaeria.

Authors:  Hyuncheol Oh; Paul R Jensen; Brian T Murphy; Catherine Fiorilla; John F Sullivan; Timothy Ramsey; William Fenical
Journal:  J Nat Prod       Date:  2010-05-28       Impact factor: 4.050

Review 6.  Terpenes from marine-derived fungi.

Authors:  Rainer Ebel
Journal:  Mar Drugs       Date:  2010-08-13       Impact factor: 5.118

7.  Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity.

Authors:  Jana A Lewis; Sarah A Scott; Robert Lavieri; Jason R Buck; Paige E Selvy; Sydney L Stoops; Michelle D Armstrong; H Alex Brown; Craig W Lindsley
Journal:  Bioorg Med Chem Lett       Date:  2009-02-20       Impact factor: 2.823

8.  Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.

Authors:  Sarah A Scott; Paige E Selvy; Jason R Buck; Hyekyung P Cho; Tracy L Criswell; Ashley L Thomas; Michelle D Armstrong; Carlos L Arteaga; Craig W Lindsley; H Alex Brown
Journal:  Nat Chem Biol       Date:  2009-01-11       Impact factor: 15.040

9.  Four eremophilane sesquiterpenes from the mangrove endophytic fungus Xylaria sp. BL321.

Authors:  Yongxiang Song; Jiajian Wang; Hongbo Huang; Lin Ma; Jun Wang; Yucheng Gu; Lan Liu; Yongcheng Lin
Journal:  Mar Drugs       Date:  2012-02-06       Impact factor: 6.085

10.  A tropical marine microbial natural products geobibliography as an example of desktop exploration of current research using web visualisation tools.

Authors:  Joydeep Mukherjee; Lyndon E Llewellyn; Elizabeth A Evans-Illidge
Journal:  Mar Drugs       Date:  2008-10-13       Impact factor: 5.118

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