PURPOSE: To develop a method for generating realistic pulmonary nodules that equal small pulmonary metastases and granulomas. MATERIALS AND METHODS: A total of 70 artificial lesions were introduced into 5 inflated porcine lungs inside a dedicated chest phantom by high pressure injection of a fat-wax-Lipiodol mixture and scanned with 16-slice computed tomography (CT). Image evaluation by two experienced radiologists included analysis of morphology, nodule size and density. RESULTS: The median nodule density was 78.8 Hounsfield units (HU), with 54 of 70 nodules (77.14 %) judged typical of small lung metastases. CONCLUSION: Without inducing visible damage of lung parenchyma, the injection technique produces highly realistic pulmonary nodules for morphometry or nodule detection with CT.
PURPOSE: To develop a method for generating realistic pulmonary nodules that equal small pulmonary metastases and granulomas. MATERIALS AND METHODS: A total of 70 artificial lesions were introduced into 5 inflated porcine lungs inside a dedicated chest phantom by high pressure injection of a fat-wax-Lipiodol mixture and scanned with 16-slice computed tomography (CT). Image evaluation by two experienced radiologists included analysis of morphology, nodule size and density. RESULTS: The median nodule density was 78.8 Hounsfield units (HU), with 54 of 70 nodules (77.14 %) judged typical of small lung metastases. CONCLUSION: Without inducing visible damage of lung parenchyma, the injection technique produces highly realistic pulmonary nodules for morphometry or nodule detection with CT.
Authors: Juergen Biederer; Tobias Gottwald; Hendrik Bolte; Christian Riedel; Sandra Freitag; Richard Van Metter; Martin Heller Journal: Eur Radiol Date: 2006-09-09 Impact factor: 5.315
Authors: M Regier; S Kandel; M G Kaul; B Hoffmann; H Ittrich; P M Bansmann; J Kemper; C Nolte-Ernsting; M Heller; G Adam; J Biederer Journal: Eur Radiol Date: 2006-09-30 Impact factor: 5.315
Authors: Tobias Achenbach; Oliver Weinheimer; Alexander Biedermann; Sabine Schmitt; Daniela Freudenstein; Edula Goutham; Richard Peter Kunz; Roland Buhl; Christoph Dueber; Claus Peter Heussel Journal: Eur Radiol Date: 2008-07-19 Impact factor: 5.315