| Literature DB >> 15380227 |
Nilesh Shah1, Thomas S Scanlan.
Abstract
A novel class of phenylpyrazole fused Wieland-Miescher ketone derivatives are high affinity, receptor specific, selective modulators of glucocorticoid receptor (GR) mediated transcription in vitro, dissociating transactivation, AP-1 repression, and NF-kappaB repression from each other.Entities:
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Year: 2004 PMID： 15380227 DOI： 10.1016/j.bmcl.2004.07.052
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823