Literature DB >> 15379719

The sodium-iodide symporter.

C H Baker1, J C Morris.   

Abstract

The sodium-iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active transport of iodide in the thyroid gland and several other extra-thyroidal tissues. This activity has been utilized for many years for imaging the thyroid gland and for treatment of thyroid disease both benign and malignant. Cloning and characterization of NIS has more recently allowed research into its use in non-thyroidal cancers through gene transfer for both diagnosis and treatment.

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Year:  2004        PMID： 15379719     DOI： 10.2174/1568008043339839

Source DB:  PubMed          Journal:  Curr Drug Targets Immune Endocr Metabol Disord        ISSN： 1568-0088


  9 in total

1.  EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy.

Authors:  Luca Giovanella; Anca M Avram; Ioannis Iakovou; Jennifer Kwak; Susan A Lawson; Elizabeth Lulaj; Markus Luster; Arnoldo Piccardo; Matthias Schmidt; Mark Tulchinsky; Frederick A Verburg; Ely Wolin
Journal:  Eur J Nucl Med Mol Imaging       Date:  2019-08-07       Impact factor: 9.236

Review 2.  The Na+/I- symporter (NIS): mechanism and medical impact.

Authors:  Carla Portulano; Monika Paroder-Belenitsky; Nancy Carrasco
Journal:  Endocr Rev       Date:  2013-12-04       Impact factor: 19.871

3.  Induction of thyroid gene expression and radioiodine uptake in melanoma cells: novel therapeutic implications.

Authors:  Peng Hou; Dingxie Liu; Meiju Ji; Zhi Liu; James M Engles; Richard L Wahl; Mingzhao Xing
Journal:  PLoS One       Date:  2009-07-10       Impact factor: 3.240

4.  Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells.

Authors:  Zhi Liu; Mingzhao Xing
Journal:  PLoS One       Date:  2012-02-16       Impact factor: 3.240

Review 5.  The sodium iodide symporter (NIS) as an imaging reporter for gene, viral, and cell-based therapies.

Authors:  Alan R Penheiter; Stephen J Russell; Stephanie K Carlson
Journal:  Curr Gene Ther       Date:  2012-02-01       Impact factor: 4.391

6.  Stimulation of cultured h9 human embryonic stem cells with thyroid stimulating hormone does not lead to formation of thyroid-like cells.

Authors:  Mykola I Onyshchenko; Igor G Panyutin; Irina V Panyutin; Ronald D Neumann
Journal:  Stem Cells Int       Date:  2012-03-11       Impact factor: 5.443

7.  The Thyroid Na+/I- Symporter: Molecular Characterization and Genomic Regulation.

Authors:  Hani Alotaibi; Merve Tuzlakoğlu-Öztürk; Uygar Halis Tazebay
Journal:  Mol Imaging Radionucl Ther       Date:  2017-02-09

8.  Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter.

Authors:  Dana Haddad; Chun-Hao Chen; Sean Carlin; Gerd Silberhumer; Nanhai G Chen; Qian Zhang; Valerie Longo; Susanne G Carpenter; Arjun Mittra; Joshua Carson; Joyce Au; Mithat Gonen; Pat B Zanzonico; Aladar A Szalay; Yuman Fong
Journal:  PLoS One       Date:  2012-08-17       Impact factor: 3.240

9.  New transgenic NIS reporter rats for longitudinal tracking of fibrogenesis by high-resolution imaging.

Authors:  Bethany Brunton; Lukkana Suksanpaisan; Hongtao Li; Qian Liu; Yinxian Yu; Alyssa Vrieze; Lianwen Zhang; Nathan Jenks; Huailei Jiang; Timothy R DeGrado; Chunfeng Zhao; Stephen J Russell; Kah-Whye Peng
Journal:  Sci Rep       Date:  2018-09-21       Impact factor: 4.379
  9 in total

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