BACKGROUND: The goals of this study were to measure the impact of cigarette smoking on cancer incidence and to determine the attributable risk of cancer due to smoking. METHODS: A cigarette smoking history was obtained from 8006 Japanese-American men examined from 1965 through 1968. After 22 years, 1389 incident cases of cancer were identified. There were 212 men with lung cancer; 202 with oral, esophageal, laryngeal, pancreatic, renal, ureteral, or bladder (oral-bladder) cancer; and 975 with cancer at other sites. RESULTS: Current smokers at time of examination had a higher incidence than nonsmokers for each of the three cancer site categories. Eighty-five percent of lung cancer cases diagnosed among current and never smokers can be attributed to cigarette smoking. The attributable risks were 46%, 16%, and 29%, respectively, for oral-bladder cancers, other cancers, and all cancers combined. In turn, the corresponding attributable risks were 60%, 26%, 13%, and 21% in comparing current smokers with past smokers. CONCLUSIONS: Current smokers can greatly reduce their risk of cancer, especially lung cancer, if they quit smoking.
BACKGROUND: The goals of this study were to measure the impact of cigarette smoking on cancer incidence and to determine the attributable risk of cancer due to smoking. METHODS: A cigarette smoking history was obtained from 8006 Japanese-American men examined from 1965 through 1968. After 22 years, 1389 incident cases of cancer were identified. There were 212 men with lung cancer; 202 with oral, esophageal, laryngeal, pancreatic, renal, ureteral, or bladder (oral-bladder) cancer; and 975 with cancer at other sites. RESULTS: Current smokers at time of examination had a higher incidence than nonsmokers for each of the three cancer site categories. Eighty-five percent of lung cancer cases diagnosed among current and never smokers can be attributed to cigarette smoking. The attributable risks were 46%, 16%, and 29%, respectively, for oral-bladder cancers, other cancers, and all cancers combined. In turn, the corresponding attributable risks were 60%, 26%, 13%, and 21% in comparing current smokers with past smokers. CONCLUSIONS: Current smokers can greatly reduce their risk of cancer, especially lung cancer, if they quit smoking.
Authors: Chyke A Doubeni; Debra P Ritzwoller; Katharine A Rendle; Andrea N Burnett-Hartman; Christine Neslund-Dudas; Robert T Greenlee; Stacey Honda; Jennifer Elston Lafata; Pamela M Marcus; Mary E Cooley; Anil Vachani; Rafael Meza; Caryn Oshiro; Michael J Simoff; Mitchell D Schnall; Elisabeth F Beaber; V Paul Doria-Rose Journal: Cancer Prev Res (Phila) Date: 2019-12-23
Authors: William G Hocking; Ping Hu; Martin M Oken; Stephen D Winslow; Paul A Kvale; Philip C Prorok; Lawrence R Ragard; John Commins; David A Lynch; Gerald L Andriole; Saundra S Buys; Mona N Fouad; Carl R Fuhrman; Claudine Isaacs; Lance A Yokochi; Thomas L Riley; Paul F Pinsky; John K Gohagan; Christine D Berg Journal: J Natl Cancer Inst Date: 2010-05-04 Impact factor: 13.506
Authors: Jeffrey S Chang; Margaret R Wrensch; Helen M Hansen; Jennette D Sison; Melinda C Aldrich; Charles P Quesenberry; Michael F Seldin; Karl T Kelsey; Rick A Kittles; Gabriel Silva; John K Wiencke Journal: Int J Cancer Date: 2008-11-01 Impact factor: 7.396