Literature DB >> 1535662

Huntington's disease: prenatal screening for late onset disease.

S G Post1.   

Abstract

This article presents a set of moral arguments regarding the selective abortion of fetuses on the basis of prenatal screening for late onset genetic diseases only, and for Huntington's Disease* in particular. After discussion of human suffering, human perfection and the distinctive features of the lives of people confronting late onset genetic disease, the author concludes that selective abortion is difficult to justify ethically, although it must remain a matter of personal choice.

Entities:  

Keywords:  Analytical Approach; Genetics and Reproduction; Abortion, Induced; Americas; Amniocentesis; Behavior; Decision Making; Demographic Factors; Developed Countries; Diseases; Economic Factors; Ethics; Examinations And Diagnoses; Family Planning; Fertility Control, Postconception; Genetic Technics; Handicapped; Hereditary Diseases; Laboratory Examinations And Diagnoses; North America; Northern America; Pain; Philosophical Overview; Population; Population Characteristics; Quality Of Life; Screening; Signs And Symptoms; Social Welfare; United States

Mesh:

Year:  1992        PMID: 1535662      PMCID: PMC1376111          DOI: 10.1136/jme.18.2.75

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  4 in total

Review 1.  Procreative liberty and human genetics.

Authors:  John A Robertson
Journal:  Emory Law J       Date:  1990

2.  A polymorphic DNA marker genetically linked to Huntington's disease.

Authors:  J F Gusella; N S Wexler; P M Conneally; S L Naylor; M A Anderson; R E Tanzi; P C Watkins; K Ottina; M R Wallace; A Y Sakaguchi
Journal:  Nature       Date:  1983 Nov 17-23       Impact factor: 49.962

3.  Two genetic markers closely linked to adult polycystic kidney disease on chromosome 16.

Authors:  S T Reeders; M H Breuning; G Corney; S J Jeremiah; P Meera Khan; K E Davies; D A Hopkinson; P L Pearson; D J Weatherall
Journal:  Br Med J (Clin Res Ed)       Date:  1986-03-29

4.  Linkage heterogeneity of autosomal dominant polycystic kidney disease.

Authors:  W J Kimberling; P R Fain; J B Kenyon; D Goldgar; E Sujansky; P A Gabow
Journal:  N Engl J Med       Date:  1988-10-06       Impact factor: 91.245

  4 in total
  3 in total

1.  Preimplantation genetic diagnosis: does age of onset matter (anymore)?

Authors:  Timothy Krahn
Journal:  Med Health Care Philos       Date:  2008-11-01

2.  Huntington disease: prenatal screening for late onset disease.

Authors:  J Greenberg
Journal:  J Med Ethics       Date:  1993-06       Impact factor: 2.903

3.  A clinical perspective on ethical arguments around prenatal diagnosis and preimplantation genetic diagnosis for later onset inherited cancer predispositions.

Authors:  Tara Clancy
Journal:  Fam Cancer       Date:  2009-07-31       Impact factor: 2.375

  3 in total

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