Literature DB >> 15341955

Synthesis and evaluation of novel oxazoline MMP inhibitors.

Gregory R Cook1, Ethirajan Manivannan, Thane Underdahl, Viera Lukacova, Yufen Zhang, Stefan Balaz.   

Abstract

MMP inhibitors with novel oxazoline zinc binding groups have been synthesized and evaluated. Selectivity for the inhibition of MMP-9 over MMP-1, MMP-2, and MMP-12 has been achieved in several cases.

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Year:  2004        PMID： 15341955     DOI： 10.1016/j.bmcl.2004.07.023

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

Review 1.  Matrix metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular disease.

Authors:  Mina M Benjamin; Raouf A Khalil
Journal:  Exp Suppl       Date:  2012

Review 2.  Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue Remodeling and Pathological Disorders.

Authors:  Jie Liu; Raouf A Khalil
Journal:  Prog Mol Biol Transl Sci       Date:  2017-05-10       Impact factor: 3.622

Review 3.  Matrix metalloproteinases as potential targets in the venous dilation associated with varicose veins.

Authors:  Arda Kucukguven; Raouf A Khalil
Journal:  Curr Drug Targets       Date:  2013-03       Impact factor: 3.465

4.  Drug-membrane interactions studied in phospholipid monolayers adsorbed on nonporous alkylated microspheres.

Authors:  Viera Lukacova; Ming Peng; Gail Fanucci; Roman Tandlich; Anne Hinderliter; Bikash Maity; Ethirajan Manivannan; Gregory R Cook; Stefan Balaz
Journal:  J Biomol Screen       Date:  2007-01-11

5.  Synthesis and evaluation of novel heterocyclic MMP inhibitors.

Authors:  Ryuji Hayashi; Xiaomin Jin; Gregory R Cook
Journal:  Bioorg Med Chem Lett       Date:  2007-10-17       Impact factor: 2.823

6.  Binding of matrix metalloproteinase inhibitors to extracellular matrix: 3D-QSAR analysis.

Authors:  Yufen Zhang; Viera Lukacova; Vladimir Bartus; Xiaoping Nie; Guorong Sun; Ethirajan Manivannan; Sandeep R Ghorpade; Xiaomin Jin; Shankar Manyem; Mukund P Sibi; Gregory R Cook; Stefan Balaz
Journal:  Chem Biol Drug Des       Date:  2008-10       Impact factor: 2.817
  6 in total

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