Literature DB >> 15338731

Object-based morphometry of the cerebral cortex.

J F Mangin1, D Rivière, A Cachia, E Duchesnay, Y Cointepas, D Papadopoulos-Orfanos, D L Collins, A C Evans, J Régis.   

Abstract

Most of the approaches dedicated to automatic morphometry rely on a point-by-point strategy based on warping each brain toward a reference coordinate system. In this paper, we describe an alternative object-based strategy dedicated to the cortex. This strategy relies on an artificial neuroanatomist performing automatic recognition of the main cortical sulci and parcellation of the cortical surface into gyral patches. A set of shape descriptors, which can be compared across subjects, is then attached to the sulcus and gyrus related objects segmented by this process. The framework is used to perform a study of 142 brains of the International Consortium for Brain Mapping (ICBM) database. This study reveals some correlates of handedness on the size of the sulci located in motor areas, which was not detected previously using standard voxel based morphometry.

Mesh:

Year:  2004        PMID: 15338731     DOI: 10.1109/TMI.2004.831204

Source DB:  PubMed          Journal:  IEEE Trans Med Imaging        ISSN: 0278-0062            Impact factor:   10.048


  44 in total

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